The Effect of Cinnamon on HbA1c Among Adolescents With Type I Diabetes
the purpose of this study is to determine if cinnamon improves glucose control among adolescents with type 1 diabetes mellitus.
|Study Design:||Allocation: Randomized
Endpoint Classification: Safety/Efficacy Study
Intervention Model: Parallel Assignment
Primary Purpose: Treatment
|Official Title:||The Effect of Cinnamon on HbA1c Among Adolescents With Type I Diabetes|
- Total Daily Insulin
- Carbohydrate/insulin dose
- Hypoglycemic events
|Study Start Date:||October 2005|
|Estimated Study Completion Date:||May 2006|
Widespread achievement of glucose control remains an elusive goal for adolescents with Type 1 diabetes. Previous research has suggested that cinnamon may be effective at improving glucose control in type 2 diabetes. To date, no research has investigated the effect of cinnamon on type 1 diabetics. If the addition of a simple, natural, pill to a standard insulin regimen can significantly improve glucose control, the clinical implications would be substantial.
Comparison: Using a prospective, double-blind, placebo-controlled design, 72 adolescent type I diabetics were treated with cinnamon (1 gram/day) or an equivalent appearing placebo for 90 days. HbA1c, total daily insulin intake, and adverse events were recorded and compared between groups.
|United States, New Hampshire|
|Dartmouth-Hitchcock Medical Center|
|Lebanon, New Hampshire, United States, 03756|
|Principal Investigator:||Samuel J Casella, MD||Dartmouth-Hitchcock Medical Center|