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Adrenal Function in Patients With Newly Diagnosed Lung Cancer

This study has been completed.
Information provided by:
Princess Margaret Hospital, Hong Kong Identifier:
First received: August 14, 2006
Last updated: January 15, 2009
Last verified: January 2009

Patients with newly diagnosed lung cancer may have hypofunction of the adrenal cortex either from tumour metastasis or other mechanisms. Since lung cancer patient may have to undergo stressful investigation and treatments, undetected hypofunction of the adrenal cortex may be hazardous. Knowledge of the size of the problem may help determine whether routine check is warranted.

Lung Cancer
Adrenal Insufficiency

Study Type: Observational
Study Design: Observational Model: Cohort
Time Perspective: Prospective
Official Title: Adrenal Cortical Function in Patients With Newly Diagnosed Lung Cancer

Resource links provided by NLM:

Further study details as provided by Princess Margaret Hospital, Hong Kong:

Enrollment: 133
Study Start Date: August 2006
Study Completion Date: May 2008
Primary Completion Date: April 2008 (Final data collection date for primary outcome measure)

Ages Eligible for Study:   18 Years and older
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Sampling Method:   Probability Sample
Study Population

Patients with newly diagnosed, histologically confirmed primary lung cancer


Inclusion Criteria:

  • Histologically proven primary lung cancer
  • Newly diagnosed
  • No specific treatment given
  • No active infection in the previous week
  • No general anesthesia in the previous week

Exclusion Criteria:

  • Known adrenal disease
  • Receiving exogenous systemic corticosteroids
  • Concomitant illness known to affect adrenal function. e.g. active TB
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its identifier: NCT00364624

China, Hong Kong SAR
Department of Medicine, Princess Margaret Hospital
Kowloon, Hong Kong SAR, China
Sponsors and Collaborators
Princess Margaret Hospital, Hong Kong
Principal Investigator: Wai C YU, MBBS Princess Margaret Hospital, Hong Kong
  More Information

No publications provided

Responsible Party: Dr. W C Yu, Consultant Physician, Princess Margaret Hospital, Hong Kong Identifier: NCT00364624     History of Changes
Other Study ID Numbers: KW/FR/06-008
Study First Received: August 14, 2006
Last Updated: January 15, 2009
Health Authority: United States: Federal Government

Keywords provided by Princess Margaret Hospital, Hong Kong:
lung cancer
adrenal insufficiency

Additional relevant MeSH terms:
Adrenal Insufficiency
Lung Neoplasms
Adrenal Gland Diseases
Endocrine System Diseases
Lung Diseases
Neoplasms by Site
Respiratory Tract Diseases
Respiratory Tract Neoplasms
Thoracic Neoplasms processed this record on November 24, 2014