Carbachol´s Headache Inducing Characteristics and Effects on the Cerebral Blood Flow - Tabular View

Tracking Information

First Received Date ^ICMJE

July 26, 2006

Last Updated Date

August 29, 2007

Start Date ^ICMJE

July 2006

Primary Completion Date

Current Primary Outcome Measures ^ICMJE

Original Primary Outcome Measures ^ICMJE

Change History

Complete list of historical versions of study NCT00357864 on ClinicalTrials.gov Archive Site

Current Secondary Outcome Measures ^ICMJE

Original Secondary Outcome Measures ^ICMJE

Descriptive Information

Brief Title ^ICMJE

Carbachol´s Headache Inducing Characteristics and Effects on the Cerebral Blood Flow

Official Title ^ICMJE

Basic Research on Carbachol´s Headache Inducing Characteristics and Effects on the Cerebral Blood Flow in a Humane Experimental Headache Model

Brief Summary

To investigate headache score and accompanying symptoms during and after infusion of carbachol.

Detailed Description

To investigate headache score and accompanying symptoms during and after infusion of carbachol.

Changes in regional cerebral blood flow (rCBF) in the area supplied by middle cerebral artery (MCA), blood flow in MCA, diameter of the superficial temporal artery (STA) and radial artery (RA)

Study Phase

Study Type ^ICMJE

Observational

Study Design ^ICMJE

Screening, Longitudinal, Convenience Sample, Prospective Study

Condition ^ICMJE

Headache

Intervention ^ICMJE

Drug: carbachol

Study Arms / Comparison Groups

Publications *

* Includes publications given by the data provider as well as publications identified by National Clinical Trials Identifier (NCT ID) in Medline.

Recruitment Information

Recruitment Status ^ICMJE

Completed

Enrollment ^ICMJE

Completion Date

April 2007

Primary Completion Date

Eligibility Criteria ^ICMJE

Inclusion Criteria:

Healthy volunteers
Aged 18-40
50-100 kg
Fertile women must use safe contraceptives (IUD, oral contraceptives, surgical sterilisation and long lasting gestagen.

Exclusion Criteria:

Tension type headache more than once/month
Other primary headaches
Daily medication except contraceptives
Drug taken within 4 times the halflife for the specific drug except contraceptives
Pregnant or lactating women
Exposure to radiation within the last year
Headache within the last 24 hours before start of trial
Hypertension
Hypotension
Respiratory or cardiac disease

Gender

Both

Ages

18 Years to 40 Years

Accepts Healthy Volunteers

Yes

Contacts ^ICMJE

Contact information is only displayed when the study is recruiting subjects

Location Countries ^ICMJE

Denmark

Administrative Information

NCT ID ^ICMJE

NCT00357864

Responsible Party

Study ID Numbers ^ICMJE

2006-002462-19

Study Sponsor ^ICMJE

Danish Headache Center

Collaborators ^ICMJE

Investigators ^ICMJE

Principal Investigator:

henrik schytz

Danish Headache Center

Information Provided By

Danish Headache Center

Verification Date

August 2007

^ICMJE Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP