CholGate - The Effect of Alerting Versus on Demand Computer Based Decision Support on Treatment of Dyslipidaemia by General Practitioners - Full Text View

Purpose

Indirect evidence show alerting physicians with clinical decision support systems (CDSS) seem to change behaviour more than requiring users to actively initiate the system. However, randomized trials comparing these methods in a clinical setting are lacking. In this study we compare the effect of Alerting physicians with a CDSS or actively requiring initiation of CDSS on the adherence of Dutch general practitioners to the Cholesterol guideline of the Dutch college of General Practitioners.

Condition	Intervention
Decision Support Systems, Clinical	Device: CholGate

Study Type:	Interventional
Study Design:	Allocation: Randomized Intervention Model: Parallel Assignment Masking: Open Label
Official Title:	The Effect of Alerting Versus on Demand Computer Based Decision Support on Treatment of Dyslipidaemia by General Practitioners - The CholGate Randomized Trial

Resource links provided by NLM:

MedlinePlus related topics: Caffeine

U.S. FDA Resources

Further study details as provided by Erasmus Medical Center:

Primary Outcome Measures:

The percentage of correctly screened patients using anonymous patient record data.
The percentage of correctly treated patients using anonymous patient record data.

Study Start Date:	June 2004
Estimated Study Completion Date:	November 2005

Detailed Description:

Indirect evidence show alerting physicians with clinical decision support systems (CDSS) seem to change behaviour more than requiring users to actively initiate the system. However, randomized trials comparing these methods in a clinical setting are lacking. In this study we compare the effect of Alerting physicians with a CDSS or actively requiring initiation of CDSS on the adherence of Dutch general practitioners to the Cholesterol guideline of the Dutch college of General Practitioners, using a clinical decsion support system called CholGate. This system has the functionality to provide both Alerting and On-Demand decision support. Users are free to negate the advise provided by the decision support system. The trial will have a cluster randomized structure.

Eligibility

Ages Eligible for Study:	18 Years to 70 Years
Genders Eligible for Study:	Both

Criteria

Inclusion Criteria:

All general practices using only Elias electronic patient records (ISOFT b.V)
All patients meeting the screening and treatment criteria of the Dutch college of general practitioners cholesterol guideline

Exclusion Criteria:

Practices that used paper based records

Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00348751

Locations

Netherlands
Department of Medical informatics, ErasmusMC
Rotterdam, South Holland, Netherlands, 3000DR

Sponsors and Collaborators

Erasmus Medical Center

Dutch Heart Foundation

Investigators

Principal Investigator:

Jacobus T van Wyk, MD, PhD

ErasmusMC University Medical Centre Rotterdam

More Information

Additional Information:

Department of medical informatics, ErasmusMC homepage This link exits the ClinicalTrials.gov site

Publications:

Van Wyk JT, Van Wijk MA, Moorman PW, Mosseveld M, Van Der Lei J. Cholgate - a randomized controlled trial comparing the effect of automated and on-demand decision support on the management of cardiovascular disease factors in primary care. AMIA Annu Symp Proc. 2003;:1040.

Van Wyk JT, Van Wijk MA. Assessment of the possibility to classify patients according to cholesterol guideline screening criteria using routinely recorded electronic patient record data. Stud Health Technol Inform. 2002;93:39-46.

Van Wyk JT, Van Wijk MA. Analysis of Dutch general practice guidelines for inconsistencies with respect to the management of cardiovascular disease risk factors. Medinfo. 2004;11(Pt 1):179-86.

van Wyk JT, Picelli G, Dieleman JP, Mozaffari E, Kramarz P, van Wijk MA, van der Lei J, Sturkenboom MC. Management of hypertension and hypercholesterolaemia in primary care in The Netherlands. Curr Med Res Opin. 2005 Jun;21(6):839-48.

Dieleman JP, van Wyk JT, van Wijk MA, van Herpen G, Straus SM, Dunselman H, Sturkenboom MC. Differences between statins on clinical endpoints: a population-based cohort study. Curr Med Res Opin. 2005 Sep;21(9):1461-8.

van Wyk JT, van Wijk MA, Sturkenboom MC, Moorman PW, van der Lei J. Identification of the four conventional cardiovascular disease risk factors by Dutch general practitioners. Chest. 2005 Oct;128(4):2521-7.

van Wyk JT, van Wijk MA, Moorman PW, van der Lei J. Cross-sectional analysis of guidelines on cardiovascular disease risk factors: going to meet the inconsistencies. Med Decis Making. 2006 Jan-Feb;26(1):57-62.

van Wyk JT, van Wijk MA, Moorman PW, Mosseveld M, van der Lei J. User Requirements Rating And Knowledge-Level Of General Practitioners At The Start Of CholGate - A Lipid Management Decision Support Project. AMIA Annu Symp Proc. 2005;:1146.

ClinicalTrials.gov Identifier:	NCT00348751 History of Changes
Other Study ID Numbers:	2000B161
Study First Received:	June 29, 2006
Last Updated:	May 7, 2008
Health Authority:	Netherlands: The Central Committee on Research Involving Human Subjects (CCMO)

Additional relevant MeSH terms:

Dyslipidemias
Lipid Metabolism Disorders
Metabolic Diseases

ClinicalTrials.gov processed this record on May 22, 2013