The Usefulness of HyperQ Recordings for the Early Diagnosis of Acute Coronary Syndrome in Patients Presenting With Chest Pain

The recruitment status of this study is unknown because the information has not been verified recently.
Verified January 2007 by Sheba Medical Center.
Recruitment status was  Recruiting
Sponsor:
Information provided by:
Sheba Medical Center
ClinicalTrials.gov Identifier:
NCT00339105
First received: June 19, 2006
Last updated: January 14, 2007
Last verified: January 2007
  Purpose

The purpose of the study is to assess the usefulness of high Frequency mid-QRS analysis in identifying the ischemic origin of patients presenting to the Emergency Room (ER)with Chest pain.


Condition Phase
Acute Coronary Syndrome
Phase 3

Study Type: Observational
Study Design: Observational Model: Defined Population
Primary Purpose: Screening
Time Perspective: Longitudinal
Official Title: The Usefulness of HyperQ Recordings for the Early Diagnosis of Acute Coronary Syndrome in Patients Presenting With Chest Pain

Resource links provided by NLM:


Further study details as provided by Sheba Medical Center:

Estimated Enrollment: 50
Study Start Date: June 2006
Estimated Study Completion Date: January 2007
Detailed Description:

Introduction:

Chest pain is the leading cause of urgent admission to the Emergency Department (ED) in western countries.Acute Coronary Syndrome(ACS) continues to be among the most difficult to predict or diagnose. Misdiagnoses may lead to discharge of patients with ACS, who should have been admitted as well as costly unnecessary hospitalizations of patients who do not have ACS.

Objectives:

To evaluate the usefulness of High Frequency mid-QRS analysis in identifying the ischemic patients out of all patients presenting to the Emergency Room (ER) with chest pain.

Comparisons:

A continuous High Frequency Mid-QRS recording will be performed using the HyperQ System (BSP Ltd.) and compared to clinical, electrophysiologic and laboratory results. The golden standards used to compare the methods will be either CT-Angio, Echocardiography or Cardiac SPECT. A follow-up inquiry will be performed after 3 months and Coronary Angiography results will be sought and compared as well.

  Eligibility

Ages Eligible for Study:   18 Years and older
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

  • Age ≥18 years
  • Patients with chest pain, with possible ACS.
  • Patients admitted to the ‘chest pain unit’
  • Chest pain appeared within 24 hours prior to admission to the ‘chest pain unit’
  • No history of trauma or any other evident medical cause of chest pain
  • Signed an Informed Consent

Exclusion Criteria:

  • Implanted pacemaker or defibrillator
  • History of trauma or other evident medical cause of chest pain
  • Patients admitted to Intensive Cardiac Care Unit or intermediate Cardiac Care Unit
  • Patients discharged from the ER
  • Patients with Bundle-Branch-Block or other intra-ventricular delay of more than 120 mSec
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT00339105

Contacts
Contact: Shlomi Matetzky, MD +972-52-6667122 shlomi.matetzky@sheba.health.gov.il

Locations
Israel
The Chest Pain Unit, ER, Sheba Medical Center, Tel-Hashomer Recruiting
Ramat-Gan, Israel
Principal Investigator: Shlomi Matetzky, MD         
Sponsors and Collaborators
Sheba Medical Center
Investigators
Principal Investigator: Shlomi Matetzky, MD Head of Chest Pain Unit, ER, Sheba Medical Center
  More Information

Additional Information:
Publications:
ClinicalTrials.gov Identifier: NCT00339105     History of Changes
Other Study ID Numbers: SHEBA-06-4114-SM-CTIL
Study First Received: June 19, 2006
Last Updated: January 14, 2007
Health Authority: Israel: Israeli Health Ministry Pharmaceutical Administration

Keywords provided by Sheba Medical Center:
Acute
Coronary
Syndrome
HyperQ
High
Frequency
ECG
chest
pain

Additional relevant MeSH terms:
Acute Coronary Syndrome
Chest Pain
Syndrome
Angina Pectoris
Cardiovascular Diseases
Disease
Heart Diseases
Myocardial Ischemia
Pain
Pathologic Processes
Signs and Symptoms
Vascular Diseases

ClinicalTrials.gov processed this record on October 23, 2014