Allograft Fibrosis Following Pediatric Cardiac Transplantation

This study has been terminated.
(unable to gather sufficient data)
Sponsor:
Information provided by:
Children's Healthcare of Atlanta
ClinicalTrials.gov Identifier:
NCT00328185
First received: May 18, 2006
Last updated: March 14, 2012
Last verified: January 2006
  Purpose

Transplantation is the preferred method of treating many forms of end-stage organ failure. While short-term results have improved, long-term outcomes remain inadequate. Myocardial fibrosis could potentially have an adverse effect on long-term cardiac function. We wish to study the degree of fibrosis to see if we can predict survival following pediatric heart transplantation.


Condition
Children Who Underwent Heart Transplantation Prior to Age 18
Received Care at Children's Healthcare of Atlanta

Study Type: Observational
Study Design: Time Perspective: Retrospective
Official Title: Allograft Fibrosis: Its Regulation and Significance Following Pediatric Cardiac Transplantation

Resource links provided by NLM:


Further study details as provided by Children's Healthcare of Atlanta:

Enrollment: 100
Study Start Date: January 2006
Study Completion Date: December 2006
  Show Detailed Description

  Eligibility

Ages Eligible for Study:   up to 18 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population

Children who underwent heart transplantation prior to age 18

Criteria

Inclusion Criteria:

  • Children who underwent heart transplantation prior to age 18
  • Followed up at Children's Healthcare of Atlanta

Exclusion Criteria:

  • Children without a transplanted heart
  • Follow-up not at children's Healthcare of Atlanta
  Contacts and Locations
Please refer to this study by its ClinicalTrials.gov identifier: NCT00328185

Locations
United States, Georgia
Children's Healthcare of Atlanta
Atlanta, Georgia, United States, 30329
Sponsors and Collaborators
Children's Healthcare of Atlanta
Investigators
Principal Investigator: Brian E Kogon, MD Emory University
  More Information

No publications provided

ClinicalTrials.gov Identifier: NCT00328185     History of Changes
Other Study ID Numbers: 05-217
Study First Received: May 18, 2006
Last Updated: March 14, 2012
Health Authority: United States: Food and Drug Administration

Keywords provided by Children's Healthcare of Atlanta:
pediatric
heart disease
orthotopic heart transplantation
allograft fibrosis

Additional relevant MeSH terms:
Fibrosis
Pathologic Processes

ClinicalTrials.gov processed this record on April 16, 2014