Randomized Trial Comparing Misoprostol and Foley Bulb for Pregnancy Termination in the Second Trimester
The purpose of this study is to compare two methods of pregnancy termination on the time to delivery in the second trimester.
Pregnancy Trimester, Second
Device: Foley bulb
|Study Design:||Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Open Label
Primary Purpose: Treatment
|Official Title:||Randomized Trial Comparing Misoprostol and Foley Bulb for Pregnancy Termination in the Second Trimester|
- Time to vaginal delivery
- Rate of chorioamnionitis
- Rate of maternal fever
- Rate of postpartum hemorrhage
|Study Start Date:||February 2005|
|Study Completion Date:||April 2007|
|Primary Completion Date:||April 2007 (Final data collection date for primary outcome measure)|
Active Comparator: Misoprostol Drug
This is the misoprostol drug.
Experimental: The Foley Bulb
This is the experimental portion to test the Foley Bulb.
|Device: Foley bulb|
Medical termination in the second trimester is performed for many indications. Successful termination is dependant on ripening of the cervix prior to labor induction. Multiple methods of cervical ripening and labor induction have been used for pregnancy termination in the second trimester. These two methods have different mechanisms of action. This study seeks to evaluate the effectiveness of these two methods.
|United States, Florida|
|Shands Hospital at the University of Florida|
|Gainesville, Florida, United States, 32610|
|Principal Investigator:||Keri A Baacke, MD||University of Florida|