The Effect of CoQ10 Administration on Hemodialysis Patients
The purpose of this study is to examine whether CoQ10 administration is effective as an antioxidant in hemodialysis patients.
|Study Design:||Allocation: Non-Randomized
Endpoint Classification: Safety Study
Intervention Model: Single Group Assignment
Masking: Open Label
Primary Purpose: Treatment
|Official Title:||The Effect of CoQ10 Administration on the Oxidative and Antioxidative Markers in Hemodialysis Patients|
- Oxidative protein concentration at 6 month
- Antioxidant capacity at 6 month
|Study Start Date:||March 2004|
|Estimated Study Completion Date:||December 2004|
Oxidative stress has been recognized as a potential risk factor for such complications as atherosclerosis in hemodialysis patients. This study investigates whether CoQ10 administration is effective for protecting oxidative stress in hemodialysis patients. The subjects were recruited from day-time hemodialysis patients in Iwata City Hospital. 100 mg CoQ10 was administered every HD for 6 months. Several oxidative and antioxidative markers were measured in plasma at pre, 1, 3, 6 months and after washout.