Feasibility Study of Phototherapy System to Treat H Pylori

Inclusion Criteria:

• Age > 18 and < 90
• Documented positive for H. pylori infection by urease breath test, stool antigen or histology within thirty days prior to procedure
• Willing to comply with study requirements
• Able to undergo endoscopic esophagogastroduodenoscopy (EGD) with biopsy

Exclusion Criteria:

• History of gastric or duodenal carcinoma
• History of prior gastric or duodenal surgery
• Oral or intravenous antibiotics use within previous one month
• Use of bismuth subsalicylate (Pepto Bismol) within previous one month
• Use of photosensitizing drugs or nutritional supplements within previous one month
• Active peptic ulcer disease (gastric or duodenal ulcer)
• Esophagitis Grade II or higher
• Oral or intravenous antibiotics use within previous one month
• History of a bleeding disorder or anti-coagulant use that would prevent biopsy
• PPI treatment two weeks prior to the scheduled endoscopy
• Positive Pregnancy Test
• Known porphyria
• Suffer from phenylketonuria (PKU)
• Signs of jaundice
• Weight < 100 lb or > 250 lb
• Previously enrolled in this study
• Participating in another ongoing clinical trial in which concomitant diagnosis or therapeutic intervention would adversely affect the integrity of this study
• The subject is inappropriate for study participation, as determined by the Investigator