Validation of the San Francisco Syncope Rule - Full Text View

Purpose

This study was designed to validate the "San Francisco Syncope Rule". This set of rules was derived by Quinn et. al. to help guide the treatment of patients evaluated in the Emergency Department who had an episode of syncope (passed out) or near syncope (almost passed out). A rule that considers patients with an abnormal ECG, a complaint of shortness of breath, hematocrit less than 30%, systolic blood pressure less than 90 mm Hg, or a history of congestive heart failure was shown predict with a good degree of accuracy which patients would have an adverse event and require admission.

Condition	Intervention
Syncope Near Syncope	Procedure: Application of the San Francisco Syncope Rule

MedlinePlus related topics:

Fainting

U.S. FDA Resources

Study Type:	Observational
Study Design:	Longitudinal, Defined Population, Prospective Study

Official Title:	Validation of the San Francisco Syncope Rule

Further study details as provided by Montefiore Medical Center:

Study Start Date:

January 2005

Detailed Description:

This study was designed to validate the "San Francisco Syncope Rule". This set of rules was derived by Quinn et. al. to help guide the treatment of patients evaluated in the Emergency Department who had an episode of syncope or near syncope.

A rule that considers patients with an abnormal ECG, a complaint of shortness of breath, hematocrit less than 30%, systolic blood pressure less than 90 mm Hg, or a history of congestive heart failure was shown predict with a good degree of accuracy which patients would have an adverse event/serious outcome and require admission. Serious outcomes include the following: death,myocardial infarction, arrhythmia, pulmonary embolism, stroke, subarachnoid hemorrhage, significant hemorrhage, or any condition causing a return ED visit and hospitalization for a related event.

In Quinn's derivation trial, the sensitivity of the rule was 96%.

Eligibility

Ages Eligible for Study:	21 Years and older
Genders Eligible for Study:	Both
Accepts Healthy Volunteers:	No

Criteria

Inclusion Criteria: Acute syncope or near syncope as a reason for the ED visit

Exclusion Criteria: Altered mental status, alcohol or illicit drug-related loss of consciousness, Definite seizure, Transient loss of consciousness caused by head trauma

Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00300625

Contacts


Contact: Adrienne J Birnbaum, MD	718-918-5814

Contact: David Esses, MD	718-920-2084	desses@montefiore.org

Locations


United States, New York
	Montefiore Medical Center	Recruiting
	Bronx, New York, United States, 10467
	Contact: David Esses, MD 718-920-2084 desses@montefiore.org
	Sub-Investigator: David Esses, MD
	Sub-Investigator: Polly E Bijur, PhD
	Sub-Investigator: Andrew Wollowitz, MD

Sponsors and Collaborators

Montefiore Medical Center

Investigators


Principal Investigator:	Adrienne J Birnbaum, MD	Albert Einstein College of Medicine of Yeshiva University

Study Chair:	E J Gallagher, MD	Montefiore Medical Center

More Information

Publications:

Quinn JV, Stiell IG, McDermott DA, Kohn MA, Wells GA. The San Francisco Syncope Rule vs physician judgment and decision making. Am J Emerg Med. 2005 Oct;23(6):782-6.

Study ID Numbers:	04-05-109C
First Received:	March 7, 2006
Last Updated:	March 7, 2006
ClinicalTrials.gov Identifier:	NCT00300625
Health Authority:	United States: Institutional Review Board

Keywords provided by Montefiore Medical Center:

Syncope

Near syncope

San Francisco Syncope rule

Study placed in the following topic categories:

Signs and Symptoms

Unconsciousness

Consciousness Disorders

Neurologic Manifestations

Neurobehavioral Manifestations

Syncope

Additional relevant MeSH terms:

Nervous System Diseases

ClinicalTrials.gov processed this record on August 28, 2008

Sponsored by:	Montefiore Medical Center
Information provided by:	Montefiore Medical Center
ClinicalTrials.gov Identifier:	NCT00300625