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Comparison of Monitors of Fluid Therapy

This study has been completed.
Sponsor:
Information provided by:
Rigshospitalet, Denmark
ClinicalTrials.gov Identifier:
NCT00286338
First received: February 1, 2006
Last updated: January 13, 2009
Last verified: January 2009
  Purpose

The investigators want to correlate different methods to guide fluid therapy. The investigators know that guidance by esophagus doppler technique has improved outcome and want to correlate other already used techniques to esophagus doppler.


Condition Phase
Hypovolemia
Phase 4

Study Type: Observational
Study Design: Time Perspective: Prospective
Official Title: Comparison of Monitors of Fluid Therapy

Further study details as provided by Rigshospitalet, Denmark:

Estimated Enrollment: 12
Study Start Date: February 2006
Study Completion Date: April 2006
Detailed Description:

Fluid therapy before and under surgery can be guided by measurement of the hearts ability to eject blood (cardiac output). By doing this it has been shown that the occurrence of nausea,vomiting and complications generally can be reduced. The function of the heart has been measured with a probe in the esophagus in in earlier studies. We want to correlate these results with other techniques by which fluid therapy also is guided in daily practice. These are: SVO2, modelflow (finapres)and NIRS.

These methods are noninvasive except SVO2 measurement which requires a central venous catheter (CVK). Therefore we have chosen a population in which CVK is standard in our institution. We thereby don´t apply any further risks than daily practice and the project is considered as a quality assessment of used standards.

  Eligibility

Ages Eligible for Study:   18 Years to 70 Years
Genders Eligible for Study:   Male
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

  • Age 18 years or older
  • Elective urological surgery in which a central venous catheter is routinely administered
  • Informed consent

Exclusion Criteria:

  • Age 70 years or older
  • No informed consent
  • Pathology in the esophagus that contraindicates use off gastric tube and esophagus doppler
  • ASA III or above
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT00286338

Locations
Denmark
Dept of anesthesia 2041, ABD centre, Rigshospitalet, Blegdamsvej
Copenhagen, Denmark, DK-2100
Sponsors and Collaborators
Rigshospitalet, Denmark
Investigators
Study Director: Henrik Kehlet, M.D., Ph.D dept of surgical patophysiology
  More Information

No publications provided

ClinicalTrials.gov Identifier: NCT00286338     History of Changes
Other Study ID Numbers: des.prost-1
Study First Received: February 1, 2006
Last Updated: January 13, 2009
Health Authority: Denmark: National Board of Health

Keywords provided by Rigshospitalet, Denmark:
Fluid therapy
Monitoring

Additional relevant MeSH terms:
Hypovolemia
Pathologic Processes

ClinicalTrials.gov processed this record on November 20, 2014