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Biomagnetic Signals of Intestinal Ischemia

This study is currently recruiting participants.
Verified January 2013 by University of South Alabama
Sponsor:
Collaborator:
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Information provided by (Responsible Party):
William Richards, University of South Alabama
ClinicalTrials.gov Identifier:
NCT00285545
First received: January 31, 2006
Last updated: January 17, 2013
Last verified: January 2013
History of Changes
  Purpose

The lack of blood flow to the small intestine causes mesenteric ischemia. Using a Superconducting QUantum Interference Device (SQUID) which measures the magnetic field of the small intestine, we are hoping to identify abnormalities without surgical intervention.


Condition Phase
Ischemia
 Phase 1

Study Type: Observational
Study Design: Observational Model: Case Control
Time Perspective: Cross-Sectional
Official Title: Biomagnetic Signals of Intestinal Ischemia II

Further study details as provided by University of South Alabama:

Primary Outcome Measures:
  • To observe a difference in the magnetic activity between normal and diseased smooth muscle [ Time Frame: 2011 ] [ Designated as safety issue: No ]

Estimated Enrollment: 60
Study Start Date: January 2000
Estimated Study Completion Date: May 2013
Primary Completion Date: January 2013 (Final data collection date for primary outcome measure)
Groups/Cohorts
Good blood flow
Group with normal blood flow to small intestine
Poor blood flow
Group with partial ischemia to small intestine

Detailed Description:

The electrical activity of the small intestine may contain important information that will help us diagnose gastrointestinal diseases. The major impediment to reducing mortality of mesenteric ischemia is the lack of a noninvasive diagnostic test that identifies the syndrome before extensive necrosis occurs. Mesenteric ischemia is caused by the lack of blood flow to the intestine. The Superconducting QUantum Interference Device (SQUID) measures the magnetic field of the intestinal smooth muscle. By comparing normal smooth muscle and that of patients with mesenteric ischemia, we hope to identify abnormal disease states without surgery.

  Eligibility

Ages Eligible for Study:   18 Years to 65 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   Yes
Sampling Method:   Non-Probability Sample
Study Population

Primary Care Clinic

Criteria

Inclusion Criteria:

  • Normal Subjects and those diagnosed with mesenteric ischemia

Exclusion Criteria:

  • Subjects who report a tendency toward claustrophobia
  Contacts and Locations
Please refer to this study by its ClinicalTrials.gov identifier: NCT00285545

Locations
United States, Tennessee
Vanderbilt University Medical Center Recruiting
Nashville, Tennessee, United States, 37232
Contact: Joan Kaiser, RN     615-343-5821     joan.kaiser@vanderbilt.edu    
Principal Investigator: William O. Richards, MD            
Sponsors and Collaborators
University of South Alabama
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Investigators
Principal Investigator: William O Richards, MD Vanderbilt University
  More Information

No publications provided

Responsible Party: William Richards, principal investigator, University of South Alabama
ClinicalTrials.gov Identifier: NCT00285545     History of Changes
Other Study ID Numbers: DK58197, R01DK058197
Study First Received: January 31, 2006
Last Updated: January 17, 2013
Health Authority: United States: Federal Government

Keywords provided by University of South Alabama:
Blood Supply
Mesentery

Additional relevant MeSH terms:
Ischemia
Pathologic Processes

ClinicalTrials.gov processed this record on May 23, 2013