Text Size

The Effect of Cold Storage Solutions on Ischemic Injury in Lung Transplantation

The recruitment status of this study is unknown because the information has not been verified recently.
Verified August 2005 by Johns Hopkins University.
Recruitment status was  Active, not recruiting
Sponsor:
Information provided by:
Johns Hopkins University
ClinicalTrials.gov Identifier:
NCT00284726
First received: January 31, 2006
Last updated: NA
Last verified: August 2005
History: No changes posted
  Purpose

The purpose of this study is to compare 2 different cold storage solutions, used to preserve donor lungs for lung transplantation, and their effect on cytokine activation related to ischemic reperfusion injury. Primary endpoint is 30 day survival.


Condition Intervention Phase
Lung Transplant Recipients
 Device: Celsior Cold Storage Solution
 Phase 3

Study Type: Interventional
Official Title: A Prospective, Controlled, Randomized Study on the Effect of Cold Storage Solutions on Complement Activation and Other Mediators of Ischemic Injury in Lung Transplantation

Resource links provided by NLM:

U.S. FDA Resources

Further study details as provided by Johns Hopkins University:

Study Start Date: December 2000
Estimated Study Completion Date: September 2005
Detailed Description:

The length of ischemic time in harvesting lung allografts is associated with graft survival. It is further thought that ischemic changes in early post-transplantation bronchoscopic biopsies has a direct correlation with later development of chronic rejection.

  Eligibility

Criteria

Inclusion Criteria:

Any patient undergoing a lung trasnplant at Johns Hopkins Hospital -

Exclusion Criteria:

-

  Contacts and Locations
Please refer to this study by its ClinicalTrials.gov identifier: NCT00284726

Sponsors and Collaborators
Johns Hopkins University
Investigators
Principal Investigator: John V. Conte, M.D. Johns Hopkins University
  More Information

No publications provided

ClinicalTrials.gov Identifier: NCT00284726     History of Changes
Other Study ID Numbers: 00-10-25-03
Study First Received: January 31, 2006
Last Updated: January 31, 2006
Health Authority: United States: Institutional Review Board

Keywords provided by Johns Hopkins University:
Cytokines in lung transplantation
Cold storage solutions
Ischemic reperfusion injury

ClinicalTrials.gov processed this record on May 16, 2013