Benefit of a Collaborative Approach to Improve the Quality of Medicines Use in Elderly Inpatients

This study has been completed.
Sponsor:
Collaborator:
Fonds National de la Recherche Scientifique
Information provided by:
Université Catholique de Louvain
ClinicalTrials.gov Identifier:
NCT00279656
First received: January 17, 2006
Last updated: NA
Last verified: June 2004
History: No changes posted
  Purpose

The purpose of this study is to evaluate the impact of a collaborative approach (geriatric care involving the collaboration with a clinical pharmacist) to optimize the prescription of medicines for elderly inpatients.


Condition Intervention Phase
Frail Elderly Inpatient
Behavioral: Pharmaceutical care
Phase 4

Study Type: Interventional
Study Design: Allocation: Randomized
Endpoint Classification: Safety/Efficacy Study
Intervention Model: Parallel Assignment
Masking: Open Label
Primary Purpose: Educational/Counseling/Training
Official Title: Collaborative Approach to Improve the Quality of Medicines Use in Elderly Inpatients - Randomized Controlled Trial

Further study details as provided by Université Catholique de Louvain:

Primary Outcome Measures:
  • Appropriateness of prescribing (using the Medication Appropriateness Index, the Beers criteria, and the ACOVE criteria of underuse) on admission, at discharge, and 3 months post-discharge

Secondary Outcome Measures:
  • Polymedication on admission, at discharge, and 1,3,12 months after discharge
  • Mortality, readmission to hospital and visit to the emergency department 1,3,12 months after discharge
  • Satisfaction with information received on medicines

Estimated Enrollment: 180
Study Start Date: November 2003
Estimated Study Completion Date: June 2005
Detailed Description:

Widespread evidence reveals frequent inadequate use of medicines in elderly patients. This includes inappropriate prescribing (overuse, underuse, misuse) that can lead to adverse drug events and drug-related admissions to hospital. In addition, when a patient is transferred from acute care settings to ambulatory care settings, discrepancies in medicines used often occur and can be hazardous.

Despite this, only limited data exist on the effectiveness of optimization strategies targeted at frail elderly inpatients.

Comparison: elderly inpatients receiving geriatric evaluation and management (GEM) care versus elderly inpatients receiving pharmaceutical care in addition to GEM care.

  Eligibility

Ages Eligible for Study:   70 Years and older
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

  • Patient admitted on the acute geriatric unit of the university teaching hospital Mont-Godinne, Belgium

Exclusion Criteria:

  • a terminal illness and life expectancy of less than 3 month
  • expected length of stay of 2 days or less
  • transfer from another unit where the patient had already been cared for by a GEM team
  • refusal to participate
  • inclusion during previous admission
  • no time for the clinical pharmacist to compound the abstracted chart within 3 days of admission
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT00279656

Locations
Belgium
Université catholique de Louvain
Brussels, Belgium, 1200
Sponsors and Collaborators
Université Catholique de Louvain
Fonds National de la Recherche Scientifique
Investigators
Principal Investigator: Anne Spinewine, MSc Université Catholique de Louvain
Study Chair: Christian Swine, MD Université Catholique de Louvain
Study Director: Paul M Tulkens, PhD Université Catholique de Louvain
  More Information

No publications provided

ClinicalTrials.gov Identifier: NCT00279656     History of Changes
Other Study ID Numbers: om050-40/2003
Study First Received: January 17, 2006
Last Updated: January 17, 2006
Health Authority: Belgium: Institutional Review Board

Keywords provided by Université Catholique de Louvain:
Frail elderly
Pharmaceutical services
Drug therapy
Geriatrics
Randomized controlled trial
Hospitals, teaching

ClinicalTrials.gov processed this record on September 11, 2014