Does Metabolic Syndrome Exist in Anorexia Nervosa?

This study has been completed.
Sponsor:
Information provided by:
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
ClinicalTrials.gov Identifier:
NCT00271921
First received: December 29, 2005
Last updated: December 17, 2012
Last verified: December 2012
  Purpose

The purpose of this study is to examine whether body fat distribution changes that occur with weight gain in women recovering from anorexia nervosa are transient or persistent, and if they are associated with other features of Metabolic Syndrome.


Condition Intervention
Anorexia Nervosa
Metabolic Syndrome
Behavioral: Calorie controlled diet

Study Type: Observational
Study Design: Observational Model: Cohort
Time Perspective: Prospective
Official Title: Does Metabolic Syndrome Exist in Anorexia Nervosa?

Resource links provided by NLM:


Further study details as provided by National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK):

Estimated Enrollment: 50
Study Start Date: September 2005
Study Completion Date: June 2007
Primary Completion Date: June 2007 (Final data collection date for primary outcome measure)
  Eligibility

Ages Eligible for Study:   18 Years to 40 Years
Genders Eligible for Study:   Female
Accepts Healthy Volunteers:   Yes
Criteria

Inclusion Criteria:

  • DSM-IV diagnosis of Anorexia Nervosa (except amenorrhea) (restricting or binge eating/purging subtype)
  • Female
  • Age 18-40
  • Medically stable
  • Participation in inpatient or daypatient treatment sufficient to restore patient to a BMI of at least 19.5kg/m²

Exclusion Criteria:

  • Additional Major Axis I disorder (including substance abuse or dependence
  • On daily prescription medication (including oral contraceptives)
  • History of suicide attempt or other self-injurious behavior within the previous 6 months
  • Significant current or past medical illness,including diabetes mellitus, heart disease
  • Indwelling metallic object (e.g., pacemaker,pump), non-removable metal jewelry or recent metallic ink tattoo
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT00271921

Locations
United States, New York
New York State Psychiatric Institute/Columbia University
New York, New York, United States, 10032
St. Luke's Roosevelt Hosptial Center
New York, New York, United States, 10025
Sponsors and Collaborators
Investigators
Principal Investigator: Laurel Mayer, MD New York State Psychiatric Institute/Columbia University
Principal Investigator: Henry Ginsberg, MD Columbia University
  More Information

No publications provided by National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Additional publications automatically indexed to this study by ClinicalTrials.gov Identifier (NCT Number):
ClinicalTrials.gov Identifier: NCT00271921     History of Changes
Other Study ID Numbers: R03 DK66033 (completed)
Study First Received: December 29, 2005
Last Updated: December 17, 2012
Health Authority: United States: Federal Government

Keywords provided by National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK):
eating disorders
anorexia nervosa
body fat distribution
metabolic syndrome
visceral adipose tissue

Additional relevant MeSH terms:
Anorexia
Anorexia Nervosa
Metabolic Syndrome X
Signs and Symptoms, Digestive
Signs and Symptoms
Eating Disorders
Mental Disorders
Insulin Resistance
Hyperinsulinism
Glucose Metabolism Disorders
Metabolic Diseases

ClinicalTrials.gov processed this record on August 28, 2014