Outcome of Crisis Intervention for Subjects With Borderline Personality Disorder or Post-Traumatic Stress Disorder

The recruitment status of this study is unknown because the information has not been verified recently.
Verified December 2005 by Laddis, Andreas, M.D..
Recruitment status was  Not yet recruiting
Sponsor:
Information provided by:
Laddis, Andreas, M.D.
ClinicalTrials.gov Identifier:
NCT00269139
First received: December 21, 2005
Last updated: February 17, 2006
Last verified: December 2005
  Purpose

Dr. Laddis will test a hypothesis about the nature and the management of behavioral crises in patients with borderline personality disorder (BPD) or post-traumatic stress disorder (PTSD). The term "behavioral crisis" is used strictly for periods of uncontrollable urges to repeat mental or outward activity, e.g., flashbacks, cutting, binging on food, drugs or sex, with no intervals to rethink one's priorities or to consider others' direction.

The clinical hypothesis states, in two steps, that:

  1. the perception of a life crisis precedes and then underlies every behavioral crisis;
  2. the behavioral crisis resolves promptly and all symptoms end if the clinicians engage the patient about his management of the life crisis that underlies the symptoms.

Condition Intervention Phase
Borderline Personality Disorder
Post-Traumatic Stress Disorders
Behavioral: Crisis resolution
Phase 1

Study Type: Interventional
Study Design: Allocation: Randomized
Endpoint Classification: Efficacy Study
Intervention Model: Parallel Assignment
Masking: Open Label
Primary Purpose: Treatment
Official Title: Study of Outcome With an Intervention From the Cape Cod Model of Psychotherapy for Subjects in a Behavioral Crisis and With the Diagnosis of Borderline Personality Disorder (BPD) or Post-Traumatic Stress Disorder (PTSD)

Resource links provided by NLM:


Further study details as provided by Laddis, Andreas, M.D.:

Primary Outcome Measures:
  • Brief Psychiatric Rating Scale (BPRS) scores
  • Scores on Client Observation and Client Interview, tools designed for this study

Secondary Outcome Measures:
  • Patient interview and ratings for the value of the clinicians' interventions
  • Staff interview and ratings for their own interventions

Estimated Enrollment: 40
Detailed Description:

Subjects in the experimental group will be treated by Dr. Laddis after their admission to a crisis stabilization unit (CSU) or to an inpatient unit (IPU) for a behavioral crisis. Subjects will be included at random, as assigned to Dr. Laddis according to his routine duties at those units.

Subjects in the control group will receive treatment for behavioral crisis according to the preference of the clinical staff at other comparable units. That treatment will constitute "treatment as usual". Clinicians in the control settings will not be informed about the experimental hypothesis, the clinical intervention and the contingent outcomes.

The subjects will be tested for the results of treatment 12-24 hours after composition of a treatment plan. The testing will be done with the Brief Psychiatric Rating Scale (BPRS), as well as with a set of criteria devised by Dr. Laddis to measure the outward behavior and the mental events during behavioral crisis. The patients and the attending frontline staff will be interviewed also about their beliefs in regard to what, among the clinicians' interventions, made a difference for the course of the behavioral crisis, for better or for worse. The raters will be trained for interrater reliability and they will not be informed about the hypothesis.

  Eligibility

Ages Eligible for Study:   19 Years to 65 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

  • Diagnosed with BPD or PTSD, with a structured interview according to the current diagnostic manual
  • In behavioral crisis

Exclusion Criteria:

  • Brain damage
  • Currently intoxicated with alcohol or drugs or in withdrawal
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT00269139

Contacts
Contact: Andreas Laddis, MD 508-320-7895 andreas.laddis@dmh.state.ma.us

Locations
United States, Massachusetts
Cape Cod and Islands Community Mental Health Center Not yet recruiting
Pocasset, Massachusetts, United States, 02559
Principal Investigator: Andreas Laddis, MD         
Sponsors and Collaborators
Laddis, Andreas, M.D.
Investigators
Principal Investigator: Andreas Laddis, MD Cape Cod and Islands Community Mental Health Center
  More Information

No publications provided

ClinicalTrials.gov Identifier: NCT00269139     History of Changes
Other Study ID Numbers: 719371
Study First Received: December 21, 2005
Last Updated: February 17, 2006
Health Authority: United States: Institutional Review Board

Keywords provided by Laddis, Andreas, M.D.:
Behavioral crisis
Perception of social crisis
Repetition compulsion
Intrusive mental events
Uncontrollable urges

Additional relevant MeSH terms:
Personality Disorders
Borderline Personality Disorder
Stress Disorders, Post-Traumatic
Stress Disorders, Traumatic
Mental Disorders
Anxiety Disorders

ClinicalTrials.gov processed this record on July 24, 2014