The Molecular Mechanism and the Role of NRAMP 1gene on Tuberculosis in Taiwan Aboriginal Tribes Population
The human homologue of mice natural-resistance-associated macrophage protein 1 (Nramp 1) gene, NRAMP 1, has been reported to play a role in the susceptibility to tuberculosis in humans. The aboriginal population in Taiwan has a 5-fold higher prevalence of tuberculosis than the Han Chinese. Whether genetic factors such as NRAMP 1 polymorphisms play a role in the prevalence of tuberculosis in Taiwanese aboriginals should be clarified.
|Study Design:||Observational Model: Case Control
Time Perspective: Longitudinal
|Official Title:||The Molecular Mechanism and the Role of NRAMP 1gene on Tuberculosis in Taiwan Aboriginal Tribes Population|
|National Health Research Institutes|
|Miaoli county, Taiwan|
|Principal Investigator:||Ih-Jen Su, M.D., Ph.D.||Division of Clinical Research, National Health Research Institutes|