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The Molecular Mechanism and the Role of NRAMP 1gene on Tuberculosis in Taiwan Aboriginal Tribes Population

This study has been completed.
Sponsor:
Information provided by:
National Health Research Institutes, Taiwan
ClinicalTrials.gov Identifier:
NCT00266383
First received: December 15, 2005
Last updated: December 16, 2005
Last verified: December 2005
History of Changes
  Purpose

The human homologue of mice natural-resistance-associated macrophage protein 1 (Nramp 1) gene, NRAMP 1, has been reported to play a role in the susceptibility to tuberculosis in humans. The aboriginal population in Taiwan has a 5-fold higher prevalence of tuberculosis than the Han Chinese. Whether genetic factors such as NRAMP 1 polymorphisms play a role in the prevalence of tuberculosis in Taiwanese aboriginals should be clarified.


Condition
Tuberculosis

Study Type: Observational
Study Design: Additional Descriptors: Psychosocial
Observational Model: Case Control
Time Perspective: Longitudinal
Time Perspective: Retrospective/Prospective
Official Title: The Molecular Mechanism and the Role of NRAMP 1gene on Tuberculosis in Taiwan Aboriginal Tribes Population

Resource links provided by NLM:

MedlinePlus related topics: Tuberculosis
U.S. FDA Resources

Further study details as provided by National Health Research Institutes, Taiwan:

Estimated Enrollment: 250
Study Start Date: January 2005
Estimated Study Completion Date: December 2005
  Eligibility

Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

  • The NRAMP 1 polymorphism of tuberculous patients in Taiwan.

Exclusion Criteria:

-

  Contacts and Locations
Please refer to this study by its ClinicalTrials.gov identifier: NCT00266383

Locations
Taiwan
National Health Research Institutes
Miaoli county, Taiwan
Sponsors and Collaborators
National Health Research Institutes, Taiwan
Investigators
Principal Investigator: Ih-Jen Su, M.D., Ph.D. Division of Clinical Research, National Health Research Institutes
  More Information

No publications provided

ClinicalTrials.gov Identifier: NCT00266383     History of Changes
Other Study ID Numbers: DOH94-DC-1009
Study First Received: December 15, 2005
Last Updated: December 16, 2005
Health Authority: Taiwan: Department of Health

Additional relevant MeSH terms:
Tuberculosis
Mycobacterium Infections
Actinomycetales Infections
Gram-Positive Bacterial Infections
Bacterial Infections

ClinicalTrials.gov processed this record on May 19, 2013