Infrared Thermography in Finding Skin Lesions in Patients With Kaposi's Sarcoma
Recruitment status was Active, not recruiting
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Purpose
RATIONALE: Diagnostic procedures, such as infrared thermography, may help find Kaposi's sarcoma and learn the extent of disease.
PURPOSE: This clinical trial is studying how well infrared thermography finds skin lesions in patients with Kaposi's sarcoma.
| Condition | Intervention |
|---|---|
|
Sarcoma |
Procedure: diagnostic imaging |
| Study Type: | Interventional |
| Study Design: | Primary Purpose: Diagnostic |
| Official Title: | Ultra-Sensitive, Infra-Red Thermographic Analysis of Kaposi's Sarcoma Skin Lesions |
| Estimated Enrollment: | 30 |
| Study Start Date: | November 2004 |
OBJECTIVES:
Primary
- Compare ultra-sensitive infrared thermographic images with visible light digital photographic images and clinical dermatologic examination as methods of measuring cutaneous lesions in patients with Kaposi's sarcoma (KS).
Secondary
- Compare differences in modulation of temperature detected in KS skin lesions with non-involved skin of the same patient and with normal skin of healthy volunteers by sequential imaging using the infrared thermographic camera.
OUTLINE: This is a controlled, pilot study.
Patients undergo clinical assessment followed by simultaneous digital photographic camera imaging and high-resolution infrared thermographic camera imaging of designated normal skin areas and selected marker lesions. Before imaging, a metal bar chilled to 0º C, 10º C, and 25º C is applied to the lesions and designated normal skin areas for up to 90 seconds.
Healthy volunteers (controls) undergo the same procedure as for the patient except only designated normal skin areas are used.
PROJECTED ACCRUAL: A total of 20 patients and 10 healthy volunteers (controls) will be accrued for this study.
Eligibility| Ages Eligible for Study: | 18 Years and older |
| Genders Eligible for Study: | Both |
| Accepts Healthy Volunteers: | No |
DISEASE CHARACTERISTICS:
Meets 1 of the following criteria:
Histologically confirmed cutaneous Kaposi's sarcoma (KS)
- At least one skin lesion accessible for imaging
- HIV positivity with proven cutaneous KS and concurrent visceral or mucous membrane involvement allowed
- Healthy volunteer (regardless of HIV status) (control)
PATIENT CHARACTERISTICS:
Performance status
- Not specified
Life expectancy
- Not specified
Hematopoietic
- Not specified
Hepatic
- Not specified
Renal
- Not specified
Other
- Pregnancy allowed
PRIOR CONCURRENT THERAPY:
- Prior topical, intralesional, or systemic treatment allowed
Contacts and Locations| United States, Maryland | |
| Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | |
| Baltimore, Maryland, United States, 21231-2410 | |
| Study Chair: | Ciro Martins, MD | Sidney Kimmel Comprehensive Cancer Center |
More Information
Additional Information:
No publications provided
| ClinicalTrials.gov Identifier: | NCT00265902 History of Changes |
| Other Study ID Numbers: | CDR0000452799, JHOC-J0429, JHOC-04080602 |
| Study First Received: | December 14, 2005 |
| Last Updated: | February 6, 2009 |
| Health Authority: | United States: Federal Government |
Keywords provided by National Cancer Institute (NCI):
|
Kaposi sarcoma |
Additional relevant MeSH terms:
|
Sarcoma, Kaposi Sarcoma Herpesviridae Infections DNA Virus Infections Virus Diseases |
Neoplasms, Connective and Soft Tissue Neoplasms by Histologic Type Neoplasms Neoplasms, Vascular Tissue |
ClinicalTrials.gov processed this record on June 13, 2013