Respiratory Mechanics and Pleural Effusion

This study has been completed.
Sponsor:
Information provided by (Responsible Party):
Davide Chiumello, Policlinico Hospital
ClinicalTrials.gov Identifier:
NCT00258518
First received: November 23, 2005
Last updated: March 7, 2012
Last verified: March 2012
  Purpose

The investigators aim to compare the respiratory mechanics in acute lung injury (ALI)/acute respiratory diseases syndrome (ARDS) patients with and without pleural effusion.


Condition Intervention
Critically Ill
Acute Lung Injury
ARDS
Procedure: mechanical ventilation/CT Scan

Study Type: Observational
Study Design: Observational Model: Cohort
Time Perspective: Prospective
Official Title: Estimation of Respiratory Mechanics (Respiratory System, Chest Wall and Lung Elastance) and Pleural Effusion at the Bedside With CT Scan.

Resource links provided by NLM:


Further study details as provided by Policlinico Hospital:

Primary Outcome Measures:
  • Role of pleural effusion and respiratory mechanics [ Time Frame: 1 hour ] [ Designated as safety issue: No ]

Enrollment: 60
Study Start Date: November 2005
Study Completion Date: June 2011
Primary Completion Date: June 2011 (Final data collection date for primary outcome measure)
Groups/Cohorts Assigned Interventions
1
ALI/ARDS patients
Procedure: mechanical ventilation/CT Scan
evaluation of pleural effusion and respiratory mechanics, CT scan

Detailed Description:

In ALI/ARDS we evaluated the respiratory mechanics (respiratory system, chest wall and lung elastance) at the bedside while pleural effusion was evaluated with CT scan. Thus we will be able to estimate any possible role of pleural effusion on the respiratory mechanics.

  Eligibility

Ages Eligible for Study:   16 Years to 90 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population

ALI/ARDS patients

Criteria

Inclusion Criteria:

  • ALI/ARDS patients underwent invasive mechanical ventilation

Exclusion Criteria:

  • Haemodynamic instability
  • Chronic obstructive pulmonary disease (COPD) patients
  Contacts and Locations
Please refer to this study by its ClinicalTrials.gov identifier: NCT00258518

Locations
Italy
Policlinico Hospital
Milano, Italy, 20122
Sponsors and Collaborators
Policlinico Hospital
Investigators
Principal Investigator: Davide Chiumello, MD Policlinico Hospital
  More Information

No publications provided

Responsible Party: Davide Chiumello, MD, Policlinico Hospital
ClinicalTrials.gov Identifier: NCT00258518     History of Changes
Other Study ID Numbers: 1500
Study First Received: November 23, 2005
Last Updated: March 7, 2012
Health Authority: Italy: National Monitoring Centre for Clinical Trials - Ministry of Health

Keywords provided by Policlinico Hospital:
Critically ill patients

Additional relevant MeSH terms:
Critical Illness
Pleural Effusion
Acute Lung Injury
Respiratory Distress Syndrome, Adult
Lung Injury
Wounds and Injuries
Disease Attributes
Pathologic Processes
Pleural Diseases
Respiratory Tract Diseases
Lung Diseases
Respiration Disorders
Thoracic Injuries

ClinicalTrials.gov processed this record on April 14, 2014