Effect of Provisional-Crown Surface Coating on Biofilm Formation

This study has been completed.
Sponsor:
Information provided by:
Hadassah Medical Organization
ClinicalTrials.gov Identifier:
NCT00254345
First received: November 15, 2005
Last updated: December 10, 2007
Last verified: December 2007
  Purpose

Auto polymerizing poly methyl methacrylate (PMMA), and light initiated resin modified PMMAs, are commonly used for fabricating provisional restorations (PRs) during prosthetic treatment 1. Biofilm accumulated on these PRs may cause caries and inflammation of the surrounding tissue, tempering the outcome of the final restoration 2. Plaque adherence to temporary restorations was significantly increased compared with the untreated reference teeth 3. Biologic and physical properties of the various materials used as PRs were studied extensively 4-8 whereas their interaction with bacterial biofilm in vivo and ex vivo is less characterized.

One improvement in provisional restorative materials is the use of liquid polish. It is claimed that these materials gives a high luster finish to provisional bis-acryl restorations and processed acrylic appliances, reduces or eliminates costly and time consuming polishing steps and can be used on all types of direct and indirect restorations and appliances.The effect of liquid polish coating or resin bonding coating on biofilm formation on PRs was not reported.


Condition Intervention Phase
Dental Plaque
Procedure: coating a dental restoration material ,polymethylmethacrylate, with liquid polish resin
Phase 1

Study Type: Interventional
Study Design: Allocation: Non-Randomized
Endpoint Classification: Efficacy Study
Intervention Model: Single Group Assignment
Masking: Open Label
Primary Purpose: Prevention
Official Title: Effect of Provisional-Crown Surface Coating on Biofilm Formation

Further study details as provided by Hadassah Medical Organization:

Primary Outcome Measures:
  • surface coating with reduced biofilm formation demonstrated by confocal scanning laser microscope and scanning electron microscope

Estimated Enrollment: 1
Study Start Date: September 2006
Study Completion Date: April 2007
Detailed Description:

Auto polymerizing poly methyl methacrylate (PMMA), and light initiated resin modified PMMAs, are commonly used for fabricating provisional restorations (PRs) during prosthetic treatment 1. Biofilm accumulated on these PRs may cause caries and inflammation of the surrounding tissue, tempering the outcome of the final restoration 2. Plaque adherence to temporary restorations was significantly increased compared with the untreated reference teeth 3. Biologic and physical properties of the various materials used as PRs were studied extensively 4-8 whereas their interaction with bacterial biofilm in vivo and ex vivo is less characterized.

One improvement in provisional restorative materials is the use of liquid polish. It is claimed that these materials gives a high luster finish to provisional bis-acryl restorations and processed acrylic appliances, reduces or eliminates costly and time consuming polishing steps and can be used on all types of direct and indirect restorations and appliances.

The effect of liquid polish coating or resin bonding coating on biofilm formation on PRs was not reported. In this study we intend to measure, in vivo early biofilm formation on PMMA PRs with and without resin coatings.

  Eligibility

Ages Eligible for Study:   18 Years and older
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   Yes
Criteria

Inclusion Criteria:

  • Patient in need for PMAA provisional crowns

Exclusion Criteria:

  • Patient took antibiotics three months prior to experiment
  Contacts and Locations
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Please refer to this study by its ClinicalTrials.gov identifier: NCT00254345

Locations
Israel
Hadassah Medical Organization,
Jerusalem,, Israel, 91120
Sponsors and Collaborators
Hadassah Medical Organization
Investigators
Study Director: Michael M Perez Davidi, DMD Hadassah Medical Organization
  More Information

Additional Information:
Publications:
ClinicalTrials.gov Identifier: NCT00254345     History of Changes
Other Study ID Numbers: 191056HMO-CTIL
Study First Received: November 15, 2005
Last Updated: December 10, 2007
Health Authority: Israel: Israeli Health Ministry Pharmaceutical Administration

Keywords provided by Hadassah Medical Organization:
biofilm
adhesion
liquid polish
bonding resin
PMMA Polymethylmetacrylate
provisional crown
no antibiotics treatment three months prior to experiment
no mouth rinse with oral solutions one month prior to experiment

Additional relevant MeSH terms:
Dental Plaque
Dental Deposits
Tooth Diseases
Stomatognathic Diseases
Polymethyl Methacrylate
Vasodilator Agents
Cardiovascular Agents
Therapeutic Uses
Pharmacologic Actions
Antimutagenic Agents
Protective Agents
Physiological Effects of Drugs

ClinicalTrials.gov processed this record on July 22, 2014