Health Impact Study of Aquatabs in Tamale, Ghana - Full Text View

Sponsor:	Centers for Disease Control and Prevention
Collaborators:	Medentech Ltd. Emory University Center for Global Safe Water NewEnergy University for Development Studies, Tamale, Ghana
Information provided by:	Centers for Disease Control and Prevention
ClinicalTrials.gov Identifier:	NCT00252928

Purpose

The purpose of this study to determine whether Aquatabs, a water treatment tablet, reduces diarrheal diseases in a peri-urban population of Tamale, Ghana.

Condition	Intervention
Diarrhea	Other: Sodium dichloroisocyanurate (NaDCC) tablets Other: Placebo

Study Type:	Interventional
Study Design:	Prevention, Randomized, Double Blind (Subject, Caregiver, Investigator), Placebo Control, Factorial Assignment, Efficacy Study
Official Title:	Health Impact Study of a Water Treatment Tablet, Aquatabs, in Tamale, Ghana

Resource links provided by NLM:

MedlinePlus related topics: Diarrhea Drinking Water

Drug Information available for: Dichloroisocyanuric acid Sodium dichloroisocyanurate

U.S. FDA Resources

Further study details as provided by Centers for Disease Control and Prevention:

Primary Outcome Measures:

Measure the impact of Aquatabs on diarrhea among persons in households in Tamale, Ghana. [ Time Frame: 12 weeks ]

Secondary Outcome Measures:

Assess the microbiological quality of household water among persons living in Tamale, Ghana. [ Time Frame: 12 weeks ]
Determine the acceptability of Aquatabs. [ Time Frame: 12 weeks ]

Enrollment:	240
Study Start Date:	July 2006
Study Completion Date:	November 2006

Arms	Assigned Interventions
A: Placebo Comparator Placebo group does not receive Aquatabs.	Other: Placebo Placebo
B: Experimental Intervention arms receives Aquatabs.	Other: Sodium dichloroisocyanurate (NaDCC) tablets Intervention arm receives NaDCC tablets to use for to disinfect their household water for use for 20L of water. Ideally, disinfection occurs every day.

Eligibility

Genders Eligible for Study:	Both
Accepts Healthy Volunteers:	Yes

Criteria

Inclusion Criteria:

Households with at least one child under 5 years old

Exclusion Criteria:

-

Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00252928

Locations

United States, Georgia
Emory University Center for Global Safe Water
Atlanta, Georgia, United States, 30322
Ghana
NewEnergy
Tamale, Ghana
University of Development Studies
Tamale, Ghana

Sponsors and Collaborators

Centers for Disease Control and Prevention

Medentech Ltd.

Emory University Center for Global Safe Water

NewEnergy

University for Development Studies, Tamale, Ghana

Investigators

Principal Investigator:	Seema Jain, MD	Centers for Disease Control and Prevention
Principal Investigator:	Robert Quick, MD	Centers for Disease Control and Prevention

More Information

Additional Information:

World Health Organization: Global Water Supply and Sanitation Assessment 2000 Report This link exits the ClinicalTrials.gov site

Centers for Disease Control and Prevention: Safe Water System This link exits the ClinicalTrials.gov site

United States Environmental Protection Agency: Product Label for Occidental Chemical Corporation Sodium Dichloroisocyanurate. This link exits the ClinicalTrials.gov site

Publications:

Mintz ED, Reiff FM, Tauxe RV. Safe water treatment and storage in the home. A practical new strategy to prevent waterborne disease. JAMA. 1995 Mar 22-29;273(12):948-53. Review.

Reiff FM, Roses M, Venczel L, Quick R, Witt VM. Low-cost safe water for the world: a practical interim solution. J Public Health Policy. 1996;17(4):389-408.

Quick RE, Venczel LV, Mintz ED, Soleto L, Aparicio J, Gironaz M, Hutwagner L, Greene K, Bopp C, Maloney K, Chavez D, Sobsey M, Tauxe RV. Diarrhoea prevention in Bolivia through point-of-use water treatment and safe storage: a promising new strategy. Epidemiol Infect. 1999 Feb;122(1):83-90.

Quick RE, Venczel LV, Gonzalez O, Mintz ED, Highsmith AK, Espada A, Damiani E, Bean NH, De Hannover EH, Tauxe RV. Narrow-mouthed water storage vessels and in situ chlorination in a Bolivian community: a simple method to improve drinking water quality. Am J Trop Med Hyg. 1996 May;54(5):511-6.

Sobel J, Mahon B, Mendoza CE, Passaro D, Cano F, Baier K, Racioppi F, Hutwagner L, Mintz E. Reduction of fecal contamination of street-vended beverages in Guatemala by a simple system for water purification and storage, handwashing, and beverage storage. Am J Trop Med Hyg. 1998 Sep;59(3):380-7.

Study ID Numbers:	CDC-NCID-4730
Study First Received:	November 10, 2005
Last Updated:	October 29, 2007
ClinicalTrials.gov Identifier:	NCT00252928 History of Changes
Health Authority:	United States: Federal Government; Ghana: University for Development Studies

Keywords provided by Centers for Disease Control and Prevention:

sodium dichloroisocyanurate
water purification
disinfection
Ghana

Additional relevant MeSH terms:

Anti-Infective Agents
Signs and Symptoms
Disinfectants
Diarrhea
Troclosene

Signs and Symptoms, Digestive
Therapeutic Uses
Antifungal Agents
Antiviral Agents
Pharmacologic Actions

ClinicalTrials.gov processed this record on November 30, 2009