Circadian Rhythms and Sleep in Familial Delayed Sleep Phase Syndrome (DSPS) and Advanced Sleep Phase Syndrome (ASPS)
The purpose of this study is to determine the properties of circadian rhythms and sleep propensity in familial advanced and delayed sleep phase syndrome (DSPS).
|Official Title:||Circadian Rhythms and Sleep in Familial DSPS and ASPS|
|Study Start Date:||September 2003|
People with delayed sleep phase syndrome (DSPS).
People with advanced sleep phase syndrome (ASPS).
Tremendous progress in the past few years has led to the identification of several circadian clock genes. This now makes it possible to determine how alterations of human circadian clock genes and their expression could lead to differences in circadian and sleep/wake cycle phenotypes. Of particular interest for understanding genetics of the human circadian system are individuals with sleep phase disorders, such as DSPS and advanced sleep phase syndrome (ASPS), because recent studies indicate a genetic basis for these disorders. While it is assumed that both ASPS and DSPS are disorders of circadian timing, little is known about how the circadian clock system, or its interaction with sleep processes, are affected in these individuals.
Participants will complete questionnaires to determine sleep quality.
|United States, Illinois|
|Chicago, Illinois, United States, 60611|
|Contact: Kathryn Reid 312-503-1528 firstname.lastname@example.org|
|Principal Investigator: Phyllis C. Zee, MD, PhD|
|Principal Investigator:||Phyllis C. Zee, MD, PhD||Northwestern University|