Long-term Observation of Patients With Early Rheumatoid Arthritis

This study is currently recruiting participants. (see Contacts and Locations)
Verified August 2011 by University of California, Los Angeles
Sponsor:
Information provided by (Responsible Party):
Harold E. Paulus, University of California, Los Angeles
ClinicalTrials.gov Identifier:
NCT00240136
First received: October 13, 2005
Last updated: August 22, 2011
Last verified: August 2011
  Purpose

The purpose of this research is to observe the effects of RA over a long period in order to learn which of the early characteristics of patients' early RA predict future joint damage and disability. We also investigate whether certain treatments can prevent or slow the development of joint damage and disability. Additionally, the costs and effects of RA on the patient are studied in order to improve the methods used to measure these effects. Clinical, demographic, radiographic, and laboratory measures are taken by the rheumatologist in the office. In addition, patient questionnaires are mailed & completed by the patient and returned to the coordinating center at UCLA. All information obtained by these means will be studied in their effects on early, severe RA.


Condition
Rheumatoid Arthritis

Study Type: Observational
Study Design: Observational Model: Cohort
Official Title: Long-term Observation of Patients With Early Rheumatoid Arthritis

Resource links provided by NLM:


Further study details as provided by University of California, Los Angeles:

Estimated Enrollment: 400
Study Start Date: January 1993
Estimated Study Completion Date: July 2023
Detailed Description:

See Publications

  Eligibility

Ages Eligible for Study:   18 Years and older
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population

Patients with rheumatoid arthritis

Criteria

Inclusion Criteria:

  • >=6 swollen joints & >=9 tender joints
  • symmetrical rheumatoid arthritis (RA)
  • <= 2 years worth of symptoms
  • rheumatoid factor seropositivity

Exclusion Criteria:

  • <18 years old
  • Inability to see rheumatologist, complete questionnaires (lack of compliance)
  • >2 years worth of symptoms
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT00240136

Contacts
Contact: Harold E Paulus, MD 310-825-6439 hpaulus@mednet.ucla.edu
Contact: Grace S Park, MPH 310-825-6333 gspark@mednet.ucla.edu

Locations
United States, California
UCLA Recruiting
Los Angeles, California, United States, 90095
Contact: Harold E Paulus, MD    310-825-6439    hpaulus@mednet.ucla.edu   
Sub-Investigator: Daniel E Furst, MD         
Sub-Investigator: Betty Tsao, PhD         
Sub-Investigator: Christina M Charles, MD         
Sub-Investigator: Veena K Ranganath, MD         
Sponsors and Collaborators
University of California, Los Angeles
Investigators
Principal Investigator: Harold E Paulus, MD University of California, Los Angeles
  More Information

Publications:

Responsible Party: Harold E. Paulus, Professor, University of California, Los Angeles
ClinicalTrials.gov Identifier: NCT00240136     History of Changes
Other Study ID Numbers: 91-10-435-32
Study First Received: October 13, 2005
Last Updated: August 22, 2011
Health Authority: United States: Institutional Review Board

Keywords provided by University of California, Los Angeles:
Early, severe

Additional relevant MeSH terms:
Arthritis
Arthritis, Rheumatoid
Joint Diseases
Musculoskeletal Diseases
Rheumatic Diseases
Connective Tissue Diseases
Autoimmune Diseases
Immune System Diseases

ClinicalTrials.gov processed this record on September 18, 2014