Spread of Dermatophytes Among Families

The recruitment status of this study is unknown because the information has not been verified recently.
Verified November 2004 by University Hospital Case Medical Center.
Recruitment status was  Recruiting
Sponsor:
Collaborator:
Novartis
Information provided by:
University Hospital Case Medical Center
ClinicalTrials.gov Identifier:
NCT00233493
First received: October 3, 2005
Last updated: NA
Last verified: November 2004
History: No changes posted
  Purpose

The objective is to demonstrate person-to-person spread of dermatophytes of the skin and nails among family members, as measured by fungal culture and DNA typing of the dermatophytes isolated.


Condition
Onychomycosis
Tinea Pedis

Study Type: Observational
Study Design: Observational Model: Defined Population
Time Perspective: Longitudinal
Official Title: Demonstration of the Spread of Dermatophytes Through Casual Contact Among Family Household Members

Resource links provided by NLM:


Further study details as provided by University Hospital Case Medical Center:

Estimated Enrollment: 150
Study Start Date: March 2005
Estimated Study Completion Date: February 2006
Detailed Description:

Enrolled families consist of at least two members over the age of 14. Once the index person is examined and a dermatophyte is isolated from either toenail or foot scale, other family members are examined and cultured. All dermatophyte isolates obtained from each family unit are compared using DNA typing and restriction length polymorphism (RFLP) to determine whether family members share the same organism or were infected by an outside source.

  Eligibility

Ages Eligible for Study:   14 Years and older
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   Yes
Criteria

Inclusion Criteria: positive dermatophyte culture

-

Exclusion Criteria:

  • use of antifungal agents, either oral or topical
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT00233493

Contacts
Contact: Mahmoud A Ghannoum, PhD 216-844-8580 mag3@case.edu
Contact: Nancy Isham, BA 216-983-3093 nancy.isham@uhhs.com

Locations
United States, Ohio
Neil Korman, MD Recruiting
Cleveland, Ohio, United States, 44106
Contact: ZsaZsa Hann    216-844-5899    zsazsa.hann@uhhs.com   
Sponsors and Collaborators
University Hospital Case Medical Center
Novartis
Investigators
Principal Investigator: Mahmoud A Ghannoum, PhD Center for Medical Mycology, University Hosp. of Cleveland
  More Information

No publications provided

ClinicalTrials.gov Identifier: NCT00233493     History of Changes
Other Study ID Numbers: CSFO327KUS16
Study First Received: October 3, 2005
Last Updated: October 3, 2005
Health Authority: United States: Institutional Review Board

Keywords provided by University Hospital Case Medical Center:
dermatophytes

Additional relevant MeSH terms:
Tinea Pedis
Tinea
Onychomycosis
Dermatomycoses
Foot Dermatoses
Foot Diseases
Infection
Mycoses
Nail Diseases
Pruritus
Signs and Symptoms
Skin Diseases
Skin Diseases, Infectious
Skin Manifestations

ClinicalTrials.gov processed this record on October 21, 2014