Use of Fish Oils to Prevent Atrial Mechanical Stunning and Atrial Remodeling Due to Atrial Arrhythmia
Recruitment status was Active, not recruiting
The purpose of this study is to investigate whether fish oils may be of benefit to patients with certain heart rhythm disturbances called atrial fibrillation and atrial flutter.
Atrial fibrillation and atrial flutter are two heart conditions that can be successfully treated in the hospital by an ablation (in the case of atrial flutter) or a cardioversion (in the case of atrial fibrillation). Ablation involves the application of high frequency energy waves to a particular spot in the heart. Cardioversion involves resetting the heart back to a normal rhythm with the use of an electric current.
Fish oil supplements may be of benefit to patients with heart problems. Recent evidence suggests that fish oils may benefit those with rhythm disturbances.
|Study Design:||Allocation: Randomized
Endpoint Classification: Safety/Efficacy Study
Intervention Model: Parallel Assignment
Masking: Open Label
Primary Purpose: Treatment
- The extent of left atrial stunning in fish oil group compared to control after reversion of atrial arrhythmias to sinus rhythm. [ Time Frame: 18 months ] [ Designated as safety issue: No ]
- Adverse events related to fish oil ingestion. [ Time Frame: 18 months ] [ Designated as safety issue: Yes ]Tolerability, mortality.
|Study Start Date:||September 2003|
|Estimated Study Completion Date:||November 2013|
|Estimated Primary Completion Date:||July 2013 (Final data collection date for primary outcome measure)|
No Intervention: Control
No fish oil
Experimental: Fish oil
Patients prescribed 6g/day of fish oil containing 1.8g EPA+DHA in a 1.5:1 ratio
|Drug: Fish oil|