Nefazodone in the Treatment of Social Phobia
The purpose of this study is to determine the effectiveness of nefazadone in patients with social anxiety disorder (SAD).
|Study Design:||Allocation: Non-Randomized
Endpoint Classification: Efficacy Study
Intervention Model: Single Group Assignment
Masking: Open Label
Primary Purpose: Treatment
|Official Title:||Nefazodone in the Treatment of Social Phobia: Functional Brain Imaging and Neuroendocrine Correlates|
The purpose of this study is to examine the efficacy of the 5HT2 receptor antagonist nefazadone in SAD, and to explore regional cerebral blood flow in patients with SAD when confronted with a personal phobic stimulus, using positron emission tomography (PET). Changes in cerebral blood flow were correlated with self-rated anxiety measures.
|United States, Georgia|
|Emory University Depatment of Psychiatry and Behavioral Sciences|
|Atlanta, Georgia, United States, 30322|
|Principal Investigator:||Charles B Nemeroff, MD, PhD||Emory University Department of Psychiatry and Behavioral Sciences|
|Study Director:||Clinton D Kilts, PhD||Emory University Department of Psychiatry and Behavioral Sciences|
|Study Director:||Jeffrey Newport, MD||Emory University Department of Psychiatry and Behavioral Sciences|