Study of Genetic Differences in People With Depression (Genetics)

This study is ongoing, but not recruiting participants.
Sponsor:
Information provided by (Responsible Party):
Andrew F. Leuchter, University of California, Los Angeles
ClinicalTrials.gov Identifier:
NCT00229463
First received: September 28, 2005
Last updated: June 18, 2012
Last verified: June 2012
  Purpose

The purpose of this study is to identify genes involved in depression. Specifically, the investigators will analyze some genes that may be related to whether or not a person responds to antidepressant medication. This project is part of basic scientific research to increase understanding of the role of genetic influences in psychological and mental processes involved in the response to treatment for depression.


Condition
Depressive Disorder, Major

Study Type: Observational
Study Design: Observational Model: Case Control
Time Perspective: Cross-Sectional
Official Title: Study of Genetic Differences in People With Depression

Resource links provided by NLM:


Further study details as provided by University of California, Los Angeles:

Estimated Enrollment: 200
Study Start Date: January 2002
  Eligibility

Ages Eligible for Study:   18 Years to 75 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   Yes
Sampling Method:   Non-Probability Sample
Study Population

Patients will be recruited from previous studies conducted at the Laboratory of Brain, Behavior, and Pharmacology, where subjects' response to treatment has already been determined. This strategy offers the advantage that no new subjects need to be enrolled in placebo-controlled treatment studies.

Criteria

Inclusion Criteria:

  • History of Unipolar Major Depression
  • Control subjects must be healthy normal adults

Exclusion Criteria:

  • Subjects with mood symptoms that are not severe enough to qualify for MDD
  • Subjects with any active medical illness that may be related to ongoing mood disorder
  • Normal subjects must be free from: a psychiatric diagnosis, substance abuse, a history of seizure disorder, and any serious medical illness
  Contacts and Locations
Please refer to this study by its ClinicalTrials.gov identifier: NCT00229463

Locations
United States, California
UCLA Semel Institute for Neuroscience and Human Behavior
Los Angeles, California, United States, 90024
Sponsors and Collaborators
University of California, Los Angeles
Investigators
Principal Investigator: Andrew F. Leuchter, M.D. University of California, Los Angeles
  More Information

Additional Information:
No publications provided

Responsible Party: Andrew F. Leuchter, Principal Investigator, University of California, Los Angeles
ClinicalTrials.gov Identifier: NCT00229463     History of Changes
Other Study ID Numbers: 01-10-049
Study First Received: September 28, 2005
Last Updated: June 18, 2012
Health Authority: United States: Institutional Review Board

Keywords provided by University of California, Los Angeles:
Depression
genetic
gene
antidepressant
research

Additional relevant MeSH terms:
Depression
Depressive Disorder
Depressive Disorder, Major
Behavioral Symptoms
Mood Disorders
Mental Disorders

ClinicalTrials.gov processed this record on April 17, 2014