Dispatcher-Assisted Resuscitation Trial (DART)

The recruitment status of this study is unknown because the information has not been verified recently.
Verified September 2005 by Public Health - Seattle and King County.
Recruitment status was  Recruiting
Information provided by:
Public Health - Seattle and King County
ClinicalTrials.gov Identifier:
First received: September 13, 2005
Last updated: NA
Last verified: September 2005
History: No changes posted

The purpose of this study is to determine whether dispatcher-assisted CPR instructions with compressions and ventilations versus dispatcher-assisted CPR instructions with compressions only improves survival from out-of-hospital cardiac arrests.

Condition Intervention Phase
Heart Arrest
Procedure: CPR with compressions & ventilations or compressions only
Phase 3

Study Type: Interventional
Study Design: Allocation: Randomized
Endpoint Classification: Efficacy Study
Intervention Model: Parallel Assignment
Masking: Open Label
Primary Purpose: Treatment
Official Title: Randomized Trial of Dispatcher-Assisted CPR:Chest Compression Alone Versus Chest Compression Plus Ventilation

Resource links provided by NLM:

Further study details as provided by Public Health - Seattle and King County:

Primary Outcome Measures:
  • Survival to hospital discharge

Secondary Outcome Measures:
  • Neurological status at hospital discharge

Estimated Enrollment: 1600
Study Start Date: June 2004
Detailed Description:

Out-of-hospital cardiac arrest, a condition characterized by a person suddenly collapsing due to heart stoppage, is a leading cause of death in the United States. In out-of-hospital cardiac arrest, survival is dependent upon what the American Heart Association has termed the chain of survival which includes quick activation of the 9-1-1 system, prompt cardiopulmonary resuscitation (CPR), early defibrillation, and qualified advanced life support care (paramedic care). CPR allows for some circulation and delivery of oxygen to vital organs when the heart is no longer beating on its own. However, in some instances, the citizen bystander has not been trained in CPR, presenting a circumstance where the cardiac arrest victim may not receive CPR until the arrival of emergency medical services (EMS) personnel (i.e., paramedics). The delay in CPR adversely affects outcome and dcreases the chance of survival. In response to this need, the EMS Division of Public Health - Seattle and King County developed and instituted telephone CPR instructions that could be provided "on-the-spot" during a cardiac arrest by the emergency medical (9-1-1) dispatcher. The instructions are designed to be given over the phone to persons who have not had previous CPR training so that they can initiate CPR prior to the arrival of EMS personnel and have been termed "dispatcher-assisted" CPR. The dispatcher instructions provided by the dispatch agencies of King County include the standard "full" CPR protocol of ventilations (breathing into the victim's mouth to inflate the lungs) and chest compressions(pumping on the patients chest to help circulate the blood). The ventilations oxygenate the blood while the chest compressions pump the oxygenated blood forward. This EMS program has led to a considerable increase in the proportion of cardiac arrest victims in King County that receive citizen bystander CPR prior to EMS arrival and has been associated with improved survival (appendix 1).

Comparison: Dispatcher-assisted CPR instructions with compressions and ventillations compared to dispatcher-assisted CPR instructions with compressions only.


Ages Eligible for Study:   9 Years and older
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No

Inclusion Criteria:

  • Cardiac arrest events where CPR is not ongoing but a bystander is willing to attempt with assistance

Exclusion Criteria:

  • Pregnancy
  • Prisoners
  • Cardiac arrest due to asphyxia, drowning, hanging, or electrocution
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT00219687

Contact: Thomas D Rea, MD, MPH 206-296-4956 rea123@u.washington.edu
Contact: Linda Culley 206-296-4693 linda.culley@metrokc.gov

United States, Washington
Thurston County Dispatch Recruiting
Olympia, Washington, United States
Contact: Joe Pellicer, MD    360-789-9050    joepellicer@comcast.net   
Sub-Investigator: Joe Pellicer, MD         
Division of Emergency Medical Services, Public Health - Seattle and King County Recruiting
Seattle, Washington, United States, 98104
Contact: Thomas D Rea, MD, MPH    206-296-4693    rea123@u.washington.edu   
Principal Investigator: Thomas D Rea, MD, MPH         
United Kingdom
London Ambulance Service Recruiting
London, England, United Kingdom
Contact: Rachael Donohoe, PhD    441183759895    lond-amb.nhs.uk   
Sub-Investigator: Rachael Donohoe, PhD         
Sponsors and Collaborators
Public Health - Seattle and King County
Principal Investigator: Thomas D Rea, MD, MPH Division of Emergency Medical Services, Public Health - Seattle and King County
Principal Investigator: Mickey S Eisenberg, MD, PhD Division of Emergency Medical Services, Public Health - Seattle and King County
  More Information

No publications provided by Public Health - Seattle and King County

Additional publications automatically indexed to this study by ClinicalTrials.gov Identifier (NCT Number):
ClinicalTrials.gov Identifier: NCT00219687     History of Changes
Other Study ID Numbers: RARC-0001-01
Study First Received: September 13, 2005
Last Updated: September 13, 2005
Health Authority: United States: Institutional Review Board

Keywords provided by Public Health - Seattle and King County:
Heart arrest
Cardiopulmonary resuscitation

Additional relevant MeSH terms:
Heart Arrest
Cardiovascular Diseases
Heart Diseases

ClinicalTrials.gov processed this record on October 20, 2014