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Dispatcher-Assisted Resuscitation Trial (DART)

This study is currently recruiting participants.
Verified by Public Health - Seattle and King County, September 2005

Sponsored by: Public Health - Seattle and King County
Information provided by: Public Health - Seattle and King County
ClinicalTrials.gov Identifier: NCT00219687
  Purpose

The purpose of this study is to determine whether dispatcher-assisted CPR instructions with compressions and ventilations versus dispatcher-assisted CPR instructions with compressions only improves survival from out-of-hospital cardiac arrests.


Condition Intervention Phase
Heart Arrest
Procedure: CPR with compressions & ventilations or compressions only
Phase III

U.S. FDA Resources

Study Type:   Interventional
Study Design:   Treatment, Randomized, Open Label, Active Control, Parallel Assignment, Efficacy Study
Official Title:   Randomized Trial of Dispatcher-Assisted CPR:Chest Compression Alone Versus Chest Compression Plus Ventilation

Further study details as provided by Public Health - Seattle and King County:

Primary Outcome Measures:
  • Survival to hospital discharge

Secondary Outcome Measures:
  • Neurological status at hospital discharge

Estimated Enrollment:   1600
Study Start Date:   June 2004

Detailed Description:

Out-of-hospital cardiac arrest, a condition characterized by a person suddenly collapsing due to heart stoppage, is a leading cause of death in the United States. In out-of-hospital cardiac arrest, survival is dependent upon what the American Heart Association has termed the chain of survival which includes quick activation of the 9-1-1 system, prompt cardiopulmonary resuscitation (CPR), early defibrillation, and qualified advanced life support care (paramedic care). CPR allows for some circulation and delivery of oxygen to vital organs when the heart is no longer beating on its own. However, in some instances, the citizen bystander has not been trained in CPR, presenting a circumstance where the cardiac arrest victim may not receive CPR until the arrival of emergency medical services (EMS) personnel (i.e., paramedics). The delay in CPR adversely affects outcome and dcreases the chance of survival. In response to this need, the EMS Division of Public Health - Seattle and King County developed and instituted telephone CPR instructions that could be provided "on-the-spot" during a cardiac arrest by the emergency medical (9-1-1) dispatcher. The instructions are designed to be given over the phone to persons who have not had previous CPR training so that they can initiate CPR prior to the arrival of EMS personnel and have been termed "dispatcher-assisted" CPR. The dispatcher instructions provided by the dispatch agencies of King County include the standard "full" CPR protocol of ventilations (breathing into the victim's mouth to inflate the lungs) and chest compressions(pumping on the patients chest to help circulate the blood). The ventilations oxygenate the blood while the chest compressions pump the oxygenated blood forward. This EMS program has led to a considerable increase in the proportion of cardiac arrest victims in King County that receive citizen bystander CPR prior to EMS arrival and has been associated with improved survival (appendix 1).

Comparison: Dispatcher-assisted CPR instructions with compressions and ventillations compared to dispatcher-assisted CPR instructions with compressions only.

  Eligibility
Ages Eligible for Study:   9 Years and older
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No

Criteria

Inclusion Criteria:

  • Cardiac arrest events where CPR is not ongoing but a bystander is willing to attempt with assistance

Exclusion Criteria:

  • Pregnancy
  • Prisoners
  • Cardiac arrest due to asphyxia, drowning, hanging, or electrocution
  Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00219687

Contacts
Contact: Thomas D Rea, MD, MPH     206-296-4956     rea123@u.washington.edu    
Contact: Linda Culley     206-296-4693     linda.culley@metrokc.gov    

Locations
United States, Washington
Division of Emergency Medical Services, Public Health - Seattle and King County     Recruiting
      Seattle, Washington, United States, 98104
      Contact: Thomas D Rea, MD, MPH     206-296-4693     rea123@u.washington.edu    
      Principal Investigator: Thomas D Rea, MD, MPH            
Thurston County Dispatch     Recruiting
      Olympia, Washington, United States
      Contact: Joe Pellicer, MD     360-789-9050     joepellicer@comcast.net    
      Sub-Investigator: Joe Pellicer, MD            
United Kingdom, England
London Ambulance Service     Recruiting
      London, England, United Kingdom
      Contact: Rachael Donohoe, PhD     441183759895     lond-amb.nhs.uk    
      Sub-Investigator: Rachael Donohoe, PhD            

Sponsors and Collaborators
Public Health - Seattle and King County

Investigators
Principal Investigator:     Thomas D Rea, MD, MPH     Division of Emergency Medical Services, Public Health - Seattle and King County    
Principal Investigator:     Mickey S Eisenberg, MD, PhD     Division of Emergency Medical Services, Public Health - Seattle and King County    
  More Information


Study ID Numbers:   RARC-0001-01
First Received:   September 13, 2005
Last Updated:   September 13, 2005
ClinicalTrials.gov Identifier:   NCT00219687
Health Authority:   United States: Institutional Review Board

Keywords provided by Public Health - Seattle and King County:
Heart arrest  
Cardiopulmonary resuscitation  
Dispatcher  

Study placed in the following topic categories:
Heart Diseases
Heart Arrest

Additional relevant MeSH terms:
Cardiovascular Diseases

ClinicalTrials.gov processed this record on December 03, 2008




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