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| Sponsors and Collaborators: |
Mayo Clinic National Institutes of Health (NIH) |
| Information provided by: | Mayo Clinic |
| ClinicalTrials.gov Identifier: | NCT00217048 |
Purpose
This study is being done to learn if yohimbine, a naturally occurring drug, affects the speed at which food travels through the stomach, intestines and colon, and if yohimbine affects the amount of liquid you can drink in a short period of time. Understanding how yohimbine works on the gut may help develop new treatments for patients with constipation. Yohimbine has been approved by the Food and Drug Administration (FDA) for routine clinical use, however, its use as proposed in this study is considered investigational.
| Condition | Intervention | Phase |
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Healthy Volunteers |
Drug: Yohimbine, oral |
Phase I Phase II |
| ChemIDplus related topics: | Yohimbine |
| Study Type: | Interventional |
| Study Design: | Treatment, Randomized, Double-Blind, Placebo Control, Parallel Assignment, Efficacy Study |
| Official Title: | Effect of Oral Yohimbine on Colonic Transit: Randomized, Placebo-Controlled Trial |
| Estimated Enrollment: | 30 |
| Study Start Date: | June 2005 |
| Estimated Study Completion Date: | October 2005 |
Eligibility
| Ages Eligible for Study: | 18 Years to 65 Years |
| Genders Eligible for Study: | Both |
| Accepts Healthy Volunteers: | Yes |
Contacts and Locations| United States, Minnesota | |||||
| Mayo Clinic | Recruiting | ||||
| Rochester, Minnesota, United States, 55905 | |||||
| Contact: Barb Seide 507-255-6802 | |||||
| Principal Investigator: Adil E Bharucha, MBBS, MD | |||||
| Mayo Clinic |
| National Institutes of Health (NIH) |
| Principal Investigator: | Adil E Bharucha, MBBS, M.D. | Mayo Clinic |
More Information
| Study ID Numbers: | 275-05 |
| First Received: | September 16, 2005 |
| Last Updated: | September 16, 2005 |
| ClinicalTrials.gov Identifier: | NCT00217048 |
| Health Authority: | United States: Institutional Review Board |
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