Study of the Effect of Cardioversion on Cardiac Volume in Patients With Persistent Atrial Fibrillation

This study has been terminated.

First Received: September 13, 2005 No Changes Posted

Sponsor:	Hvidovre University Hospital
Collaborators:	The Foundation of 17.12.1981 The A.P. Moeller Foundation for the Advancement of Medical Science Danish Hospital Foundation for Medical Research, Region of Copenhagen Danish Heart Foundation Copenhagen Hospital Corporation
Information provided by:	Hvidovre University Hospital
ClinicalTrials.gov Identifier:	NCT00209911

Purpose

The main objectives in this study were to examine the cardiac structural and functional changes in patients with persistent and permanent AF, with the aim of improving our understanding of the underlying pathophysiological mechanisms. In addition we aimed to identify variables predictive of recurrent AF.

Condition	Intervention
Atrial Fibrillation	Procedure: cardioversion

Study Type:	Observational
Study Design:	Natural History, Longitudinal, Convenience Sample, Prospective Study
Official Title:	Atrial and Ventricular Volume and Function In Atrial Fibrillation - A Magnetic Resonance Imaging Study

Resource links provided by NLM:

Genetics Home Reference related topics: Brugada syndrome familial atrial fibrillation short QT syndrome

MedlinePlus related topics: Atrial Fibrillation MRI Scans

U.S. FDA Resources

Further study details as provided by Hvidovre University Hospital:

Estimated Enrollment:	60
Study Start Date:	January 2001
Estimated Study Completion Date:	January 2003

Eligibility

Genders Eligible for Study:	Both
Accepts Healthy Volunteers:	Yes

Criteria

Inclusion Criteria:

Exclusion Criteria:

severe pulmonary or renal disease
contraindications to magnetic resonance imaging
valvular disease
previous cardiac surgery

Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00209911

Locations

Denmark
Dept. of Cardiology, Copenhagen University Hospital Hvidovre
Hvidovre, Denmark, 2650

Sponsors and Collaborators

Hvidovre University Hospital

The Foundation of 17.12.1981

The A.P. Moeller Foundation for the Advancement of Medical Science

Danish Hospital Foundation for Medical Research, Region of Copenhagen

Danish Heart Foundation

Copenhagen Hospital Corporation

Investigators

Principal Investigator:

Susette Krohn Therkelsen, MD, phd

Unaffiliated

More Information

Publications:

Therkelsen SK, Groenning BA, Svendsen JH, Jensen GB. Atrial and ventricular volume and function in persistent and permanent atrial fibrillation, a magnetic resonance imaging study. J Cardiovasc Magn Reson. 2005;7(2):465-73.

Study ID Numbers:	susette_phd
Study First Received:	September 13, 2005
Last Updated:	September 13, 2005
ClinicalTrials.gov Identifier:	NCT00209911 History of Changes
Health Authority:	Denmark: The Regional Committee on Biomedical Research Ethics

Keywords provided by Hvidovre University Hospital:

atrial volume
ventricular volume
atrial function
ventricular function

magnetic resonance imaging
cardioversion
natriuretic peptides

Additional relevant MeSH terms:

Pathologic Processes
Heart Diseases
Cardiovascular Diseases
Atrial Fibrillation
Arrhythmias, Cardiac

ClinicalTrials.gov processed this record on February 08, 2010