Airway Inflammation in Swimmers

This study has been completed.
Sponsor:
Collaborators:
Imperial College London
Sygekassernes Helsefond
Toyota-Fonden
Team Denmark
Anti Doping Danmark
Ragnhild Ibsens Legat for Medicinsk Forskning
Kong Christian IX og Dronning Louises Jubilæumslegat
Kong Christian den Tiendes Fond
Information provided by:
Bispebjerg Hospital
ClinicalTrials.gov Identifier:
NCT00207038
First received: September 14, 2005
Last updated: February 10, 2009
Last verified: February 2009
  Purpose

Studies have shown that the prevalence of respiratory symptoms, airway hyperresponsiveness (AHR) and asthma is high and increasing in elite athletes. The inflammation seen in the airways of elite athletes might differ from the inflammation seen in the airways of "ordinary" asthmatics and it might represent a different kind of asthma.

The primary purposes are

  1. To investigate the type of airway inflammation in young swimmers.
  2. To investigate the acute changes in airway inflammation after a short training session.

Condition
Asthma

Study Type: Observational
Study Design: Observational Model: Cohort
Time Perspective: Cross-Sectional
Official Title: Airway Inflammation in Swimmers: Development and Risk Factors

Resource links provided by NLM:


Further study details as provided by Bispebjerg Hospital:

Biospecimen Retention:   Samples Without DNA

Blood samples EBC Sputum


Estimated Enrollment: 90
Study Start Date: September 2005
Study Completion Date: February 2009
  Eligibility

Ages Eligible for Study:   10 Years to 16 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   Yes
Sampling Method:   Non-Probability Sample
Study Population

Elite swimmers

Criteria

Inclusion Criteria:

  • Swimmer

Exclusion Criteria:

  • Current smoker or more than 3 pack-years
  Contacts and Locations
Please refer to this study by its ClinicalTrials.gov identifier: NCT00207038

Locations
Denmark
Respiratory and Allergy Research Unit, Department of Internal Medicine, Bispebjerg Hospital, University Hospital of Copenhagen
Copenhagen, Denmark, 2400
Sponsors and Collaborators
Bispebjerg Hospital
Imperial College London
Sygekassernes Helsefond
Toyota-Fonden
Team Denmark
Anti Doping Danmark
Ragnhild Ibsens Legat for Medicinsk Forskning
Kong Christian IX og Dronning Louises Jubilæumslegat
Kong Christian den Tiendes Fond
Investigators
Study Chair: Lars Pedersen, MD Respiratory and Allergy Reseach Unit, Department of Internal Medicine, Bispebjerg Bakke 23, Bispebjerg Hospital, University Hospital of Copenhagen, DK-2400 Copenhagen NV, Denmark
  More Information

No publications provided

Responsible Party: Lars Pedersen, Bispebjerg Hospital
ClinicalTrials.gov Identifier: NCT00207038     History of Changes
Other Study ID Numbers: (KF) 01 261528
Study First Received: September 14, 2005
Last Updated: February 10, 2009
Health Authority: Denmark: Ethics Committee

Keywords provided by Bispebjerg Hospital:
Asthma
Airway inflammation
Sport

Additional relevant MeSH terms:
Asthma
Inflammation
Bronchial Diseases
Respiratory Tract Diseases
Lung Diseases, Obstructive
Lung Diseases
Respiratory Hypersensitivity
Hypersensitivity, Immediate
Hypersensitivity
Immune System Diseases
Pathologic Processes

ClinicalTrials.gov processed this record on April 15, 2014