Photodynamic Therapy of Acne Vulgaris - a Randomized Blinded Controlled Study

This study has been completed.
Information provided by:
Bispebjerg Hospital Identifier:
First received: September 12, 2005
Last updated: October 10, 2006
Last verified: October 2004

The purpose of the study is to evaluated the efficacy and tolerability of methyl aminolevulinate and 5-aminolevulinic acid photodynamic therapy in patients with moderate to severe facial acne vulgaris in a randomized controlled and investigator blinded trial.

Condition Intervention
Acne Vulgaris
Procedure: Photodynamic therapy

Study Type: Interventional
Study Design: Allocation: Randomized
Endpoint Classification: Safety/Efficacy Study
Intervention Model: Parallel Assignment
Masking: Single Blind
Primary Purpose: Treatment

Resource links provided by NLM:

Further study details as provided by Bispebjerg Hospital:

Primary Outcome Measures:
  • Lesion counts (non-inflammatory and inflammatory)
  • Leeds Revised Acne Grading System

Secondary Outcome Measures:
  • Pain
  • Side effects

Estimated Enrollment: 24
Study Start Date: November 2004

Ages Eligible for Study:   18 Years and older
Genders Eligible for Study:   Both

Inclusion Criteria:18 years or older, good health, more than 12 inflammatory facial acne lesions -

Exclusion Criteria:skin type VI, pregnant or lactating woman. Oral retinoid use within one year, systemic antibiotics within 1 month, topical acne treatment within 2 weeks.


  Contacts and Locations
Please refer to this study by its identifier: NCT00206895

Bispebjerg Hospital
Copenhagen, Copenhagen NV, Denmark, 2400
Sponsors and Collaborators
Bispebjerg Hospital
Study Director: Hans Christian Wulf, MD, Sci Bispebjerg Hospital
  More Information

No publications provided Identifier: NCT00206895     History of Changes
Other Study ID Numbers: KF-01-177/04
Study First Received: September 12, 2005
Last Updated: October 10, 2006
Health Authority: Denmark: The Ministry of the Interior and Health

Additional relevant MeSH terms:
Acne Vulgaris
Acneiform Eruptions
Skin Diseases
Facial Dermatoses
Sebaceous Gland Diseases processed this record on April 16, 2014