Haloperidol vs. Risperidone in the Treatment of Aggression in Psychotic Inmates

This study has been terminated.
Sponsor:
Collaborator:
Janssen Pharmaceutica N.V., Belgium
Information provided by:
University of Connecticut Health Center
ClinicalTrials.gov Identifier:
NCT00203775
First received: September 12, 2005
Last updated: October 12, 2006
Last verified: May 2005
  Purpose

This study examines the efficacy of haldol versus risperdal in the treatment of aggression in psychotic prison inmates. It is hypothsized that risperdal will be more effective in decreasing aggression than haldol.


Condition Intervention
Psychosis
Aggression
Drug: risperidone

Study Type: Interventional
Study Design: Allocation: Randomized
Endpoint Classification: Efficacy Study
Intervention Model: Parallel Assignment
Masking: Double-Blind
Primary Purpose: Treatment
Official Title: Efficacy of Risperidone Versus Haloperidol in the Treatment of Aggression and Hostility in Psychotic Inmates

Resource links provided by NLM:


Further study details as provided by University of Connecticut Health Center:

Study Start Date: July 2002
Estimated Study Completion Date: April 2004
  Eligibility

Ages Eligible for Study:   18 Years and older
Genders Eligible for Study:   Both
Criteria

Inclusion Criteria:age 18 or over, psychotic disorder diagnosed on SCID, inmate at correctional facility for at least 2 weeks -

Exclusion Criteria: active withdrawal from substances of abuse, non-psychotic individuals, pregnant women, people unable to give informed consent, patients on mood stabilizers

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  Contacts and Locations
Please refer to this study by its ClinicalTrials.gov identifier: NCT00203775

Locations
United States, Connecticut
University of connecticut health center
Farmington, Connecticut, United States, 06030
Sponsors and Collaborators
University of Connecticut
Janssen Pharmaceutica N.V., Belgium
Investigators
Principal Investigator: catherine f lewis, md University of Connecticut Health Center
  More Information

No publications provided

ClinicalTrials.gov Identifier: NCT00203775     History of Changes
Other Study ID Numbers: RIS-USA-269, IRB Project Number 01-250, RIS-USA-T255
Study First Received: September 12, 2005
Last Updated: October 12, 2006
Health Authority: United States: Food and Drug Administration

Additional relevant MeSH terms:
Aggression
Mental Disorders
Psychotic Disorders
Behavioral Symptoms
Schizophrenia and Disorders with Psychotic Features
Haloperidol
Haloperidol decanoate
Risperidone
Antiemetics
Autonomic Agents
Peripheral Nervous System Agents
Physiological Effects of Drugs
Pharmacologic Actions
Central Nervous System Agents
Therapeutic Uses
Gastrointestinal Agents
Antipsychotic Agents
Tranquilizing Agents
Central Nervous System Depressants
Psychotropic Drugs
Dopamine Antagonists
Dopamine Agents
Neurotransmitter Agents
Molecular Mechanisms of Pharmacological Action
Anti-Dyskinesia Agents
Serotonin Antagonists
Serotonin Agents

ClinicalTrials.gov processed this record on April 17, 2014