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Research Network for Neonatal Diseases Induced by Tissular Fetomaternal Alloimmunization

The recruitment status of this study is unknown because the information has not been verified recently.
Verified September 2005 by University Hospital, Limoges.
Recruitment status was  Recruiting
Sponsor:
Information provided by:
University Hospital, Limoges
ClinicalTrials.gov Identifier:
NCT00199628
First received: September 14, 2005
Last updated: March 10, 2006
Last verified: September 2005
History of Changes
  Purpose

Problems of compatibility between a mother and her child are frequent. The most well-known case can be illustrated by the fetomaternal blood group incompatibility (rhesus factor) which can induce severe anemia of the fetus.

The investigators recently proved that incompatibility between mother and child can concern an organ leading to a tissular alloimmunization. For example, neonatal membranous glomerulonephritis (a kidney disease) can result from this mechanism.

The purpose of this network is to detect and study neonatal diseases induced by tissular fetomaternal alloimmunization. The detection of these diseases will be performed by the mother's serum analysis.


Condition
Glomerulonephritis, Membranous
Neonatal Diseases and Abnormalities
Hemochromatosis

Study Type: Observational
Study Design: Observational Model: Defined Population
Time Perspective: Longitudinal
Time Perspective: Prospective
Official Title: Research Network for Neonatal Diseases Induced by Tissular Fetomaternal Alloimmunization

Resource links provided by NLM:

U.S. FDA Resources

Further study details as provided by University Hospital, Limoges:

Estimated Enrollment: 100
Study Start Date: September 2005
  Eligibility

Genders Eligible for Study:   Female
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

Mothers having a child suffering from:

  • Neonatal membranous glomerulonephritis
  • Unexplained neonatal tubular defect
  • Unexplained thrombotic microangiopathy
  • Neonatal hemochromatosis

Exclusion Criteria:

  • Any cause explaining the child's disease
  Contacts and Locations
Please refer to this study by its ClinicalTrials.gov identifier: NCT00199628

Contacts
Contact: Vincent Guigonis, MD +33(0)555 056 358 vincent.guigonis@chu-limoges.fr

Locations
France
Limoges University Hospital Recruiting
Limoges, France, 87042
Contact: Vincent Guigonis, MD     +33(0) 555 056 358     vincent.guigonis@chu-limoges.fr    
Principal Investigator: Vincent Guigonis, MD            
Sponsors and Collaborators
University Hospital, Limoges
Investigators
Principal Investigator: Vincent Guigonis, MD Department of Pediatrics, Limoges University Hospital
  More Information

No publications provided

ClinicalTrials.gov Identifier: NCT00199628     History of Changes
Other Study ID Numbers: I05001
Study First Received: September 14, 2005
Last Updated: March 10, 2006
Health Authority: France: Ministry of Health

Keywords provided by University Hospital, Limoges:
fetomaternal tissular alloimmunization
Mothers having a child suffering from:
neonatal membranous glomerulonephritis
 unexplained neonatal tubular defect
unexplained thrombotic microangiopathy
neonatal hemochromatosis

Additional relevant MeSH terms:
Hemochromatosis
Congenital Abnormalities
Glomerulonephritis
Glomerulonephritis, Membranous
Infant, Newborn, Diseases
Nephritis
Kidney Diseases
Urologic Diseases
 Autoimmune Diseases
Immune System Diseases
Metal Metabolism, Inborn Errors
Metabolism, Inborn Errors
Genetic Diseases, Inborn
Iron Overload
Iron Metabolism Disorders
Metabolic Diseases

ClinicalTrials.gov processed this record on May 21, 2013