Text Size

The Serotonergic Transmitter System in Dementia and Affective Disorders

The recruitment status of this study is unknown because the information has not been verified recently.
Verified September 2005 by Rigshospitalet, Denmark.
Recruitment status was  Recruiting
Sponsor:
Information provided by:
Rigshospitalet, Denmark
ClinicalTrials.gov Identifier:
NCT00192998
First received: September 13, 2005
Last updated: September 26, 2007
Last verified: September 2005
History of Changes
  Purpose

The aim of this project is to examine the serotonergic transmitter system using functional imaging of the brain (positron emission tomography [PET]) to gain knowledge about early pathophysiological changes in Alzheimer's dementia and mood disorders.


Condition
Mood Disorders
Alzheimer Disease

Study Type: Observational
Study Design: Observational Model: Defined Population
Observational Model: Natural History
Time Perspective: Cross-Sectional
Time Perspective: Prospective

Resource links provided by NLM:

U.S. FDA Resources

Further study details as provided by Rigshospitalet, Denmark:

Estimated Enrollment: 100
Study Start Date: October 2003
  Eligibility

Ages Eligible for Study:   18 Years and older
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   Yes
Criteria

Inclusion Criteria:

  • Moderate to severe Alzheimer's disease
  • Individuals genetically predisposed to affective disorder
  • Healthy gender and age matched controls

Exclusion Criteria:

  • Contraindications to magnetic resonance imaging (MRI)
  • Use of psychoactive drugs
  • Past or present affective disorder
  • Other systemic diseases that may affect brain function
  Contacts and Locations
Please refer to this study by its ClinicalTrials.gov identifier: NCT00192998

Contacts
Contact: Vibe G. Frokjaer, MD +45 3545 6714 vibe@nru.dk
Contact: Steen G. Hasselbalch, MD sgh@nru.dk

Locations
Denmark
Neurobiological Research Unit Recruiting
Copenhagen, Denmark, 2100
Contact: Vibe G. Frokjaer, MD     +45 3545 6714     vibe@nru.dk    
Principal Investigator: Vibe G. Frokjaer, MD            
Sponsors and Collaborators
Rigshospitalet, Denmark
Investigators
Principal Investigator: Vibe G. Frokjaer, MD Neurobiological Research Unit, Copenhagen University Hospital, Denmark
  More Information

Additional Information:
homepage for the neurobiological research unit, Copenhagen, Denmark  This link exits the ClinicalTrials.gov site

No publications provided

ClinicalTrials.gov Identifier: NCT00192998     History of Changes
Other Study ID Numbers: SERT-AD
Study First Received: September 13, 2005
Last Updated: September 26, 2007
Health Authority: Denmark: Ethics Committee

Keywords provided by Rigshospitalet, Denmark:
Affective disorder
Alzheimer dementia
healthy controls

Additional relevant MeSH terms:
Alzheimer Disease
Mood Disorders
Dementia
Brain Diseases
Central Nervous System Diseases
 Nervous System Diseases
Tauopathies
Neurodegenerative Diseases
Delirium, Dementia, Amnestic, Cognitive Disorders
Mental Disorders

ClinicalTrials.gov processed this record on May 22, 2013