Magnetic Resonance (MR) in Asthmatic Patients

This study has suspended participant recruitment.
(no funding)
Sponsor:
Information provided by:
University Health Network, Toronto
ClinicalTrials.gov Identifier:
NCT00188487
First received: September 12, 2005
Last updated: April 20, 2007
Last verified: April 2007
  Purpose

Asthma is a disease of small airways. Affected areas have reduced lung ventilation causing reflex vasoconstriction. MR perfusion imaging of the lungs is a sensitive method of imaging zonal lung perfusion.


Condition Intervention Phase
Asthma
Device: magnetic resonance imaging (MRI) of the thorax
Phase 1

Study Type: Interventional
Study Design: Allocation: Non-Randomized
Endpoint Classification: Efficacy Study
Intervention Model: Single Group Assignment
Masking: Open Label
Primary Purpose: Diagnostic
Official Title: MR Perfusion Imaging in Asthmatic Patients

Resource links provided by NLM:


Further study details as provided by University Health Network, Toronto:

Primary Outcome Measures:
  • The correlation of MR lung perfusion analysis with computed tomography (CT) findings and pulmonary function tests

Estimated Enrollment: 80
Study Start Date: September 2005
Estimated Study Completion Date: December 2005
Detailed Description:

A cohort of 70 Asthmatic Patients and 10 controls, both sets of subjects have HRCT, MRI/A of the Thorax, and Pulmonary Function Tests to correlate the degree of pulmonary dysfunction with findings on imaging tests.

  Eligibility

Ages Eligible for Study:   16 Years and older
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   Yes
Criteria

Inclusion Criteria:

  • All asthmatic patients are eligible.

Exclusion Criteria:

  • Patients in whom MRI is contraindicated
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT00188487

Locations
Canada, Ontario
Toronto General Hospital
Toronto, Ontario, Canada
Sponsors and Collaborators
University Health Network, Toronto
Investigators
Principal Investigator: Narinder Paul, FRCP C University Health Network, Toronto
  More Information

No publications provided

ClinicalTrials.gov Identifier: NCT00188487     History of Changes
Other Study ID Numbers: 05-0174
Study First Received: September 12, 2005
Last Updated: April 20, 2007
Health Authority: Canada: Health Canada

Additional relevant MeSH terms:
Asthma
Bronchial Diseases
Respiratory Tract Diseases
Lung Diseases, Obstructive
Lung Diseases
Respiratory Hypersensitivity
Hypersensitivity, Immediate
Hypersensitivity
Immune System Diseases

ClinicalTrials.gov processed this record on July 22, 2014