Determination of Voiding Patterns of Children With Vesicoureteral Reflux

This study is enrolling participants by invitation only.
Information provided by (Responsible Party):
Linda Dairiki Shortliffe, Stanford University Identifier:
First received: September 13, 2005
Last updated: June 17, 2013
Last verified: June 2013

Determine if the pattern of voiding differs in children with vesicoureteral reflux (VUR) compared to those who do not have VUR.

Vesicoureteral Reflux

Study Type: Observational [Patient Registry]
Study Design: Time Perspective: Prospective
Target Follow-Up Duration: 12 Months
Official Title: Determination of Voiding Patterns of Children With Vesicoureteral Reflux

Resource links provided by NLM:

Further study details as provided by Stanford University:

Primary Outcome Measures:
  • Uroflow rate [ Time Frame: 3 months ] [ Designated as safety issue: No ]
    Obtain pre and postoperative uroflow after VUR correction

Secondary Outcome Measures:
  • PVR [ Time Frame: 3 months ] [ Designated as safety issue: No ]
    Pre and postoperative measures

Estimated Enrollment: 250
Study Start Date: June 2005
Estimated Study Completion Date: December 2015
Estimated Primary Completion Date: July 2015 (Final data collection date for primary outcome measure)
Detailed Description:

We hope to determine the statistical difference between the flow rate and volume of urination in children with VUR compared to those without.


Ages Eligible for Study:   3 Years to 16 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   Yes
Sampling Method:   Non-Probability Sample
Study Population

Children with history of vesicoureteral reflux, toilet trained, ambulatory, and able to void on command. Children scheduled to have procedural correction of vesicoureteral reflux


Inclusion Criteria:

  • Children with or without vesicoureteral reflux (history of VUR)
  • Toilet trained and can void on command

Exclusion Criteria:

  • Any voiding disorder, musculoskeletal neurologic disorders, other congenital or acquired genitourinary problems, growth disorders, recent UTI
  Contacts and Locations
Please refer to this study by its identifier: NCT00186199

United States, California
Lucile Packard Childrens Hospital
Stanford, California, United States, 94305
Sponsors and Collaborators
Stanford University
Principal Investigator: Linda Shortliffe, MD Department of Urology, Stanford University
  More Information

No publications provided

Responsible Party: Linda Dairiki Shortliffe, Professor Urology, Stanford University Identifier: NCT00186199     History of Changes
Other Study ID Numbers: 1790
Study First Received: September 13, 2005
Last Updated: June 17, 2013
Health Authority: United States: Institutional Review Board

Keywords provided by Stanford University:
voiding patterns
flow rate

Additional relevant MeSH terms:
Gastroesophageal Reflux
Vesico-Ureteral Reflux
Esophageal Motility Disorders
Deglutition Disorders
Esophageal Diseases
Gastrointestinal Diseases
Digestive System Diseases
Urinary Bladder Diseases
Urologic Diseases processed this record on April 16, 2014