Trial record 17 of 2166 for:    Open Studies | "Hematologic Diseases"

Bone Marrow Grafting for Leukemia and Lymphoma

This study is currently recruiting participants. (see Contacts and Locations)
Verified June 2014 by Stanford University
Sponsor:
Collaborators:
Information provided by (Responsible Party):
Stanford University
ClinicalTrials.gov Identifier:
NCT00186147
First received: September 13, 2005
Last updated: June 18, 2014
Last verified: June 2014
  Purpose

The purpose of this study is to obtain tissue samples for ongoing studies regarding transplant outcomes and complications.


Condition Intervention
Leukemia
Lymphoma
Hematologic Diseases
Procedure: collection and storage of tissue samples for research

Study Type: Observational
Study Design: Observational Model: Cohort
Time Perspective: Prospective
Official Title: Bone Marrow Grafting for Leukemia and Lymphoma

Resource links provided by NLM:


Further study details as provided by Stanford University:

Primary Outcome Measures:
  • Identify and characterize proteins and genes that may contribute to the development and progression of cancer. [ Time Frame: blood sample is collected prior transplant, periodically during the first three months and then indefinately at follow up ] [ Designated as safety issue: No ]

Biospecimen Retention:   Samples With DNA

Tissue samples will be obtained from subjects undergoing transplantation or donors providing the graft.


Estimated Enrollment: 9999
Study Start Date: March 1988
Estimated Study Completion Date: December 2019
Estimated Primary Completion Date: December 2018 (Final data collection date for primary outcome measure)
Groups/Cohorts Assigned Interventions
Graft recipients and donors Procedure: collection and storage of tissue samples for research
Tissue samples include blood draws for the donor and recipient. A bone marrow sample may be obtained from the recipient. If the recipient undergoes a tissue biopsy for clinical reasons, a small fraction may be removed for research purposes. A small fraction of the donor graft may be removed at the time of collection for research.

Detailed Description:

The purpose of this study is to obtain tissue samples for ongoing studies regarding transplant outcomes and complications.

  Eligibility

Ages Eligible for Study:   up to 70 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population

All hematopoietic cell transplant recipients and donors who agree to participate

Criteria

Inclusion Criteria:- All hematopoietic cell transplant recipients and donors who agree to participate

Exclusion Criteria:- Subject does not agree to participate

  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT00186147

Contacts
Contact: Physician Referrals (650) 723-0822

Locations
United States, California
Stanford University School of Medicine Recruiting
Stanford, California, United States, 94305
Contact: Physician Referrals    650-723-0822      
Principal Investigator: David Miklos         
Principal Investigator: Robert S Negrin         
Sub-Investigator: Judith Anne Shizuru         
Sub-Investigator: Laura Johnston         
Sub-Investigator: Sandra Jeane Horning         
Sub-Investigator: Karl G. Blume         
Sponsors and Collaborators
Stanford University
Investigators
Principal Investigator: David Miklos Stanford University
Principal Investigator: Robert S Negrin Stanford University
  More Information

No publications provided

Responsible Party: Stanford University
ClinicalTrials.gov Identifier: NCT00186147     History of Changes
Other Study ID Numbers: BMT19, 13358, BMT19
Study First Received: September 13, 2005
Last Updated: June 18, 2014
Health Authority: United States: Institutional Review Board

Additional relevant MeSH terms:
Hematologic Diseases
Leukemia
Lymphoma
Neoplasms by Histologic Type
Neoplasms
Lymphoproliferative Disorders
Lymphatic Diseases
Immunoproliferative Disorders
Immune System Diseases

ClinicalTrials.gov processed this record on August 26, 2014