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Depression Prevention Program for Adolescents

This study has been completed.
Sponsor:
Collaborator:
Information provided by (Responsible Party):
University of Texas at Austin
ClinicalTrials.gov Identifier:
NCT00183417
First received: September 13, 2005
Last updated: April 23, 2012
Last verified: April 2012
  Purpose

This study will compare the effectiveness of two programs designed to prevent depression in adolescents.


Condition Intervention
Depression
Behavioral: Cognitive behavior therapy (CBT)
Behavioral: Supportive/expressive (S/E) therapy
Behavioral: Bibliotherapy

Study Type: Interventional
Study Design: Allocation: Randomized
Endpoint Classification: Efficacy Study
Intervention Model: Parallel Assignment
Masking: Open Label
Primary Purpose: Prevention
Official Title: Depression Prevention Program for High-Risk Adolescents

Further study details as provided by University of Texas at Austin:

Primary Outcome Measures:
  • Depressive symptoms [ Time Frame: Measured at Year 1 ] [ Designated as safety issue: No ]

Enrollment: 350
Study Start Date: September 2004
Study Completion Date: May 2009
Primary Completion Date: May 2009 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Experimental: 1
Participants will receive cognitive behavioral therapy
Behavioral: Cognitive behavior therapy (CBT)
Participants will complete worksheets and group discussion on how to increase positive mood and activity.
Active Comparator: 2
Participants will receive supportive/expressive therapy
Behavioral: Supportive/expressive (S/E) therapy
Participants will be encouraged to express feelings and emotions without advice giving.
Active Comparator: 3
Participants will receive bibliotherapy
Behavioral: Bibliotherapy
Participants will be given a book on how to increase their mood.
No Intervention: 4
Participants in the control condition will receive no treatment

Detailed Description:

Major depression is one of the most common psychiatric disorders in adolescents. In many cases, the condition is recurrent and can result in serious psychological impairment. A high number of depressed adolescents never receive treatment; therefore, it is crucial to develop prevention programs for this disorder that are effective and can be easily disseminated. This study will evaluate and compare the effectiveness of cognitive behavior therapy (CBT) and supportive/expressive (S/E) therapy in preventing depressive symptoms in adolescents.

This study will last 2 years. Participants will be randomly assigned to receive six sessions of CBT, S/E therapy, or standard depression education over 2 years. The CBT intervention will focus on reducing negative thoughts and increasing engagement in pleasant activities. S/E therapy is designed to allow adolescents to express their negative emotions and talk about recent stressful events in a supportive environment of their peers. Surveys and psychiatric interviews will be completed by all participants and their parents at the beginning and the end of the study. The surveys and interviews will assess depressive symptoms.

  Eligibility

Ages Eligible for Study:   14 Years to 18 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   Yes
Criteria

Inclusion Criteria:

  • Beck Depression Inventory score higher than 10
  • Parent or guardian willing to provide informed consent

Exclusion Criteria:

  • Diagnosis of depression
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT00183417

Locations
United States, Texas
University of Texas at Austin
Austin, Texas, United States, 78712
Sponsors and Collaborators
University of Texas at Austin
Investigators
Principal Investigator: Eric M. Stice, PhD University of Texas at Austin
  More Information

Additional Information:
No publications provided by University of Texas at Austin

Additional publications automatically indexed to this study by ClinicalTrials.gov Identifier (NCT Number):
Responsible Party: University of Texas at Austin
ClinicalTrials.gov Identifier: NCT00183417     History of Changes
Other Study ID Numbers: R01 MH67183, R01MH067183, DSIR 84-CTP
Study First Received: September 13, 2005
Last Updated: April 23, 2012
Health Authority: United States: Federal Government

Keywords provided by University of Texas at Austin:
Adolescent
CBT

Additional relevant MeSH terms:
Depression
Depressive Disorder
Behavioral Symptoms
Mental Disorders
Mood Disorders

ClinicalTrials.gov processed this record on November 25, 2014