Efficacy of Transdermal Fentanyl for Chronic Neuropathic Pain
The efficacy of fentanyl TTS for the treatment of neuropathic pain remains to be established, although opioids in general are clearly effective for neuropathic pain and fentanyl TTS has been shown to be effective for treating other types of pain. We propose to measure functional outcomes, pain relief and side effects of fentanyl TTS for the treatment of neuropathic pain. Measures will be made at baseline and after titrating the drug to an effective level.
Peripheral Neuropathy, CRPS1 and Postamputation Pain.
Drug: Transdermal Fentanyl
|Study Design:||Allocation: Non-Randomized
Endpoint Classification: Safety/Efficacy Study
Intervention Model: Single Group Assignment
Masking: Open Label
Primary Purpose: Treatment
- Change in pain intensity (0-10) and daily activity
- Pain relief (0-100%)
- Cognition (digital symbol and grooved peg-board)
- Impairment of function (MPI) and affect (BDI)
|Study Start Date:||October 2003|
|Estimated Study Completion Date:||September 2005|