Effect of Deep Brain Stimulation on Depression and Quality of Life in Parkinson’s Patients
We will evaluate the effect of deep brain stimulation on the depression and quality of life in Parkinson’s disease. We aim to compare depression pre-operatively and post-operatively in Parkinson’s patients with deep brain stimulation to Parkinson’s patients evaluated and approved for deep brain stimulation but who did not complete surgery. We will also compare quality of life measures between patients with and without deep brain stimulation.
|Study Design:||Observational Model: Defined Population
Primary Purpose: Screening
Time Perspective: Longitudinal
|Official Title:||Effect of Deep Brain Stimulation on Depression and Quality of Life in Parkinson’s Patients|
|Study Start Date:||April 2004|
|Estimated Study Completion Date:||November 2005|
Deep brain stimulation is an approved therapy for Parkinson’s patients, and this procedure is actively performed at Vanderbilt University Hospital. Questions have been raised concerning the effect of deep brain stimulation on the depression commonly seen in Parkinson’s patients. Through this study, we plan to evaluate and compare the incidence and severity of depression in Parkinson’s patients with deep brain stimulation to those who did not complete the surgery. Primary literature has indicated a general increase in quality of life of those patients receiving DBS, but no studies have compared these two specific patient populations.
Please refer to this study by its ClinicalTrials.gov identifier: NCT00179101
|United States, Tennessee|
|Nashville, Tennessee, United States, 37212|
|Principal Investigator:||Courtney R Schadt, BS||Vanderbilt University|
|Study Director:||David Charles, MD||Vanderbilt University|