Repository: Evaluation of Immunoregulatory Cells in Hematopoietic Stem Cell Transplant

This study has been completed.
Sponsor:
Information provided by:
Vanderbilt University
ClinicalTrials.gov Identifier:
NCT00179075
First received: September 13, 2005
Last updated: December 12, 2008
Last verified: December 2008
  Purpose

This is a repository to store blood and stem cell samples for future research.


Condition
Hematopoietic Stem Cell Transplantation
Graft vs Host Disease

Study Type: Observational
Study Design: Observational Model: Case-Only
Time Perspective: Prospective
Official Title: Repository for Study: Evaluation of Immunoregulatory Cells in Hematopoietic Stem Cell Transplant (HSCT)

Resource links provided by NLM:


Further study details as provided by Vanderbilt University:

Estimated Enrollment: 100
Study Start Date: April 2003
Study Completion Date: April 2008
Detailed Description:

Our Hypothesis is that the graft-versus-tumor effect can be enhanced while minimizing the complications of GVHD by determining the qualitative and quantitative changes in T regulatory cells throughout the transplant process. Our understanding of this can lead to new treatment strategies and improved clinical therapeutic implications.

  Eligibility

Ages Eligible for Study:   18 Years to 70 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population

Patients 18-70 years old undergoing either autologous transplant or allogeneic transplant for various hematologic conditions

Criteria

Inclusion Criteria:

  • Patients 18-70 years old undergoing either autologous transplant or allogeneic transplant for various hematologic conditions

Exclusion Criteria:

  • Patients < 18 or > 70 years old undergoing either autologous transplant or allogeneic transplant
  Contacts and Locations
Please refer to this study by its ClinicalTrials.gov identifier: NCT00179075

Locations
United States, Tennessee
Vanderbilt University Medical Center
Nashville, Tennessee, United States, 37232
Sponsors and Collaborators
Vanderbilt University
Investigators
Principal Investigator: Adetola A Kassim, MD Vanderbilt University
  More Information

No publications provided

Responsible Party: Adetola A. Kassim, MD, Vanderbilt University
ClinicalTrials.gov Identifier: NCT00179075     History of Changes
Other Study ID Numbers: BMT 030263
Study First Received: September 13, 2005
Last Updated: December 12, 2008
Health Authority: United States: Institutional Review Board

Keywords provided by Vanderbilt University:
T-Lymphocyte Subsets

Additional relevant MeSH terms:
Graft vs Host Disease
Immune System Diseases

ClinicalTrials.gov processed this record on April 17, 2014