Realistic Models of Gastrointestinal Bioelectromagnetism (SQUID)

The recruitment status of this study is unknown because the information has not been verified recently.
Verified June 2011 by Vanderbilt University.
Recruitment status was  Recruiting
Sponsor:
Information provided by:
Vanderbilt University
ClinicalTrials.gov Identifier:
NCT00178997
First received: September 13, 2005
Last updated: June 24, 2011
Last verified: June 2011
  Purpose

The purpose of this study is to look at the electrical activity present in healthy and diseased smooth muscle of the intestines; and develop both mathematical and computer models.


Condition Phase
Ischemia
Phase 1

Study Type: Observational
Study Design: Observational Model: Case Control
Time Perspective: Cross-Sectional
Official Title: Realistic Models of Gastrointestinal Bioelectromagnetism

Further study details as provided by Vanderbilt University:

Primary Outcome Measures:
  • To observe a difference in the electrical activity between normal and diseased smooth muscle of the intestines. [ Time Frame: 2011 ] [ Designated as safety issue: No ]

Secondary Outcome Measures:
  • To create both mathematical and computer models of the electrical activity of the intestines. [ Time Frame: 2011 ] [ Designated as safety issue: No ]

Estimated Enrollment: 60
Study Start Date: February 2004
Estimated Study Completion Date: July 2011
Groups/Cohorts
Good blood flow
Group without ischemia to the small intestine
Poor blood flow
Groups that have partial ischemia to their small intestine

Detailed Description:

The Superconducting QUantum Interference Device (SQUID)is a large cylinder machine located in a large shielded room that measures magnetic activity of the intestines. Subjects will be asked to lie underneath and get recordings of the electrical activity of their intestines. They will also be asked to have a CT scan done. From these two procedures, the mathematical and computer models will be developed to determine the difference between normal bowels and those that do not have adequate blood supply.

  Eligibility

Ages Eligible for Study:   18 Years to 65 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   Yes
Sampling Method:   Non-Probability Sample
Study Population

Primary Care Clinic

Criteria

Inclusion Criteria:

  • Normal subjects and those with diseased bowel

Exclusion Criteria:

  • Subjects with claustrophobia
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT00178997

Contacts
Contact: Alan Bradshaw, PhD 615-322-0705 alan.bradshaw@vanderbilt.edu

Locations
United States, Tennessee
Vanderbilt UNiversity Medical Center Recruiting
Nashville, Tennessee, United States, 37232
Contact: Joan Kaiser, RN    615-343-5821    joan.kaiser@vanderbilt.edu   
Contact: William O Richards, MD    615-322-7555    bill.richards@vanderbilt.edu   
Principal Investigator: Andrew J Pullan, PhD         
Sponsors and Collaborators
Vanderbilt University
Investigators
Principal Investigator: Andrew J Pullan Vanderbilt University
  More Information

No publications provided

Responsible Party: Andrew Pullan, Vanderbilt University
ClinicalTrials.gov Identifier: NCT00178997     History of Changes
Other Study ID Numbers: 040014, 5RO1DK64775-02
Study First Received: September 13, 2005
Last Updated: June 24, 2011
Health Authority: United States: Federal Government

Keywords provided by Vanderbilt University:
Blood supply
Mesentery

ClinicalTrials.gov processed this record on September 16, 2014