Measuring Alterations of DNA in Human Blood

This study has been completed.
Sponsor:
Collaborator:
Litron Laboratories
Information provided by:
University of Rochester
ClinicalTrials.gov Identifier:
NCT00178308
First received: September 12, 2005
Last updated: September 6, 2006
Last verified: September 2006
  Purpose

The purpose of this research is to evaluate an automated, laser-based technique for measuring DNA damge resulting from radiation. We want to use controlled exposure on cancer patients to help develop a measurement to test people who may have been accidentally exposed to radiation.


Condition
Neoplasms

Study Type: Observational
Study Design: Observational Model: Defined Population
Time Perspective: Longitudinal

Further study details as provided by University of Rochester:

Estimated Enrollment: 24
  Eligibility

Ages Eligible for Study:   21 Years to 70 Years
Genders Eligible for Study:   Both
Criteria

Inclusion Criteria:

  • Male or female, age 21 to 70 years old.
  • Patient undergoing with anti-neoplastic agent(s) known to have genotoxic activity (e.g., cyclophosphamide, 5-FU, cisplatin, Ara-C.
  • X-irradiation may be considered, so long as a substantial fraction of red marrow is exposed (e.g., femur or chest/trunk region);
  • treatment could be ongoing therapy or initial therapy.
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT00178308

Locations
United States, New York
University of Rochester
Rochester, New York, United States
Sponsors and Collaborators
University of Rochester
Litron Laboratories
Investigators
Principal Investigator: Yuhchyau Chen, MD, Ph.D Universtiy of Rochester, Dept of Radiation Oncology
  More Information

No publications provided

ClinicalTrials.gov Identifier: NCT00178308     History of Changes
Other Study ID Numbers: URCC 1702
Study First Received: September 12, 2005
Last Updated: September 6, 2006
Health Authority: United States: Institutional Review Board

ClinicalTrials.gov processed this record on October 01, 2014