Atopic Dermatitis-Like Skin Disease in Pediatric Heart Transplant Patients
This study has been terminated.
(IRB approval has lapsed.)
Information provided by (Responsible Party):
University of Minnesota - Clinical and Translational Science Institute ( Hordinsky, Maria K., MD )
First received: September 12, 2005
Last updated: February 1, 2013
Last verified: February 2013
The skin disease found in pediatric heart transplant patients represents an atopic dermatitis-like rash that is refractory to systemic immunomodulation.
Procedure: Skin Biopsy
||Atopic Dermatitis-Like Skin Disease in Pediatric Heart Transplant Patients
| Estimated Enrollment:
| Study Start Date:
| Study Completion Date:
| Primary Completion Date:
||January 2007 (Final data collection date for primary outcome measure)
Procedure: Skin Biopsy
Other Name: Skin biopsy.
We want to determine whether pediatric heart transplant patients with an atopic dermatitis-like rash report a personal and/or family history of atopy (asthma, allergies and atopic dermatitis). In addition comparisons will be made between the presence of atopy between patients with and without the skin rash. Comparisons will be made of systemic immunosuppressive therapies between patients with and without the atopic dermatitis-like rash. Determination will be made as to whether histologic characterization of a skin biopsy specimen is consistent with AD. Thorough evaluations will be made of patients in the clinic with this rash and the presence of bacterial superinfection will be ruled out.
|Ages Eligible for Study:
||up to 16 Years
|Genders Eligible for Study:
|Accepts Healthy Volunteers:
- Patients must have had a heart transplant.
- Patients must be less than 16 years of age.
- Patients who have not had a heart transplant.
- Patients who are greater than 16 years of age.
Please refer to this study by its ClinicalTrials.gov identifier: NCT00176956
|University of Minnesota
|Minneapolis, Minnesota, United States, 55455 |
Hordinsky, Maria K., MD
||Maria Hordinsky, MD
||University of Minnesota - Clinical and Translational Science Institute
No publications provided
||University of Minnesota - Clinical and Translational Science Institute ( Hordinsky, Maria K., MD )
History of Changes
|Other Study ID Numbers:
|Study First Received:
||September 12, 2005
||February 1, 2013
||United States: Institutional Review Board
Keywords provided by University of Minnesota - Clinical and Translational Science Institute:
Post Pediatric Heart Transplant
Additional relevant MeSH terms:
ClinicalTrials.gov processed this record on March 05, 2014
Skin Diseases, Genetic
Genetic Diseases, Inborn
Skin Diseases, Eczematous
Immune System Diseases