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Images in Extracranial Artery Stenosis

The recruitment status of this study is unknown because the information has not been verified recently.
Verified September 2005 by National Taiwan University Hospital.
Recruitment status was  Recruiting
Sponsor:
Information provided by:
National Taiwan University Hospital
ClinicalTrials.gov Identifier:
NCT00173927
First received: September 12, 2005
Last updated: October 29, 2007
Last verified: September 2005
History of Changes
  Purpose

The goals of this trial are:

  1. To compare the sensitivity and specificity of various tools including Doppler and magnetic resonance imaging (MRI) for diagnosing vertebral artery stenosis and carotid artery stenosis. The positron emission tomography (PET)/MRI fusion imaging will be a promising tool to provide both anatomical and functional imaging for vulnerable plaques.
  2. To identify patients at high risk of plaque rupture by image studies, biomedical profile, and gene expression of circulating monocytes.

Condition
Extracranial Atherosclerosis

Study Type: Observational
Study Design: Time Perspective: Prospective
Official Title: The Differences in Images of Vertebral Artery Stenosis and Carotid Artery Stenosis Pre- and Post-Percutaneous Transluminal Angioplasty and the Gene Expression Patterns in Peripheral White Blood Cells

Resource links provided by NLM:

MedlinePlus related topics: Atherosclerosis
U.S. FDA Resources

Further study details as provided by National Taiwan University Hospital:

Estimated Enrollment: 100
Study Start Date: March 2004
  Eligibility

Ages Eligible for Study:   30 Years to 90 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

  • Patients with symptomatic extracranial atherosclerosis who are going to receive angiography and possible intervention.

Exclusion Criteria:

  • Acute systemic illness
  • Creatinine > 3 mg/dl
  • Unable to tolerate the tests (including MRI and PET/computed tomography [CT] scans)
  Contacts and Locations
Please refer to this study by its ClinicalTrials.gov identifier: NCT00173927

Contacts
Contact: Hsien-Li Kao, MD 886-2-2312-3456 ext 2152 hsienli_kao@yahoo.com

Locations
Taiwan
National Taiwan University Hospital Recruiting
Taipei, Taiwan, 10012
Contact: Hsien-Li Kao, MD     886-2-2312-3456 ext 2152     hsienli_kao@yahoo.com    
Sponsors and Collaborators
National Taiwan University Hospital
Investigators
Principal Investigator: Hsien-Li Kao, MD National Taiwan University Hospital
  More Information

No publications provided

ClinicalTrials.gov Identifier: NCT00173927     History of Changes
Other Study ID Numbers: 9261701156, NTUH 94N04
Study First Received: September 12, 2005
Last Updated: October 29, 2007
Health Authority: Taiwan: Department of Health

Keywords provided by National Taiwan University Hospital:
extracranial atherosclerosis
imaging
biomarkers

Additional relevant MeSH terms:
Atherosclerosis
Carotid Stenosis
Vertebrobasilar Insufficiency
Arteriosclerosis
Arterial Occlusive Diseases
Vascular Diseases
Cardiovascular Diseases
 Carotid Artery Diseases
Cerebrovascular Disorders
Brain Diseases
Central Nervous System Diseases
Nervous System Diseases
Brain Ischemia

ClinicalTrials.gov processed this record on May 23, 2013