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Effects of Tai Chi Exercise on Innate and Adaptive Immune Function

This study is currently recruiting participants.
Verified by National Taiwan University Hospital, December 2004

Sponsors and Collaborators: National Taiwan University Hospital
National Science Council, Taiwan
Information provided by: National Taiwan University Hospital
ClinicalTrials.gov Identifier: NCT00172679
  Purpose

Tai Chi is a traditional Chinese martial art that has been practiced for many centuries. Improvements in cardiorespiratory function, balance, muscular strength, flexibility in older subjects; preventing falls in the frail elderly; stress reduction, and mood state with Tai Chi practices have been well established. A potential immune response effect of Tai Chi practice is a frequent claim; however, this is an under-researched area. Therefore, in this study, the researchers will examine the effects of Tai Chi on innate and adaptive immune function.


Condition
Healthy

MedlinePlus related topics:   Exercise and Physical Fitness   

U.S. FDA Resources

Study Type:   Observational
Study Design:   Natural History, Cross-Sectional, Defined Population, Retrospective/Prospective Study

Further study details as provided by National Taiwan University Hospital:

Estimated Enrollment:   30
Study Start Date:   July 2005
Estimated Study Completion Date:   June 2006

Detailed Description:

Tai Chi, a traditional Chinese martial art that has been practiced for many centuries, has only recently gained the interest of researchers in Western countries as an alternative form of exercise. Tai Chi combines deep diaphragmatic breathing and relaxation with many fundamental postures that flow imperceptibly and smoothly from one to the other through slow, gentle, and graceful movements. Based on the maximum oxygen consumption (VO2max) measured during the practice, Tai Chi is characterized as a low- to moderate-intensity form of exercise. Tai Chi has been applied as a rehabilitation program in patients with heart failure, hypertension, acute myocardial infarction, arthritis, and multiple sclerosis. Improvements in cardiorespiratory function, balance, muscular strength, flexibility in older subjects; preventing falls in the frail elderly; stress reduction, and mood state with Tai Chi practices have been well established. A potential immune response effect of Tai Chi practice is a frequent claim; however, this is an under-researched area. A nonrandomized controlled study of 60 elderly subjects found that the total number of circulating T cells were significantly higher in the Tai Chi group (who regularly practiced Tai Chi for 4 or more years) than in the untrained group. Irwin et al. demonstrated that older adults with no previous Tai Chi experience after practicing for 15 wks (1-3 times/wk), a nearly 50% increase in varicella zoster virus specific, cell-mediated immunity was found. Thus in this proposed study, we will examine the effects of regular Tai Chi practitioners on innate and adaptive immune function.

  Eligibility
Ages Eligible for Study:   30 Years to 70 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   Yes

Criteria

Inclusion Criteria:

  • Has been practicing Tai Chi Chuan (TCC) for at least 3 days a week for at least 12 months.

Exclusion Criteria:

  • Any chronic systemic diseases (e.g., coronary artery disease [CAD])
  • Has cognitive impairments.
  Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00172679

Contacts
Contact: Li-Ying Wang, Ph.D.     886-223123456 ext 6683     liying@ntu.edu.tw    

Locations
Taiwan
National Taiwan University Hospital     Not yet recruiting
      Taipei, Taiwan, 100
      Contact: Li-Ying Wang, Ph.D.     886-223123456 ext 6683     liying@ntu.edu.tw    
School & Graduate Institute of Physical Therapy, College of Medicine, NTU     Recruiting
      Taipei, Taiwan, 100
      Contact: Li-Ying Wang, Ph.D.     886-2-23123456 ext 6683     liying@ntu.edu.tw    

Sponsors and Collaborators
National Taiwan University Hospital
National Science Council, Taiwan

Investigators
Principal Investigator:     Li-Ying Wang, Ph.D.     National Taiwan University, College of Medicine    
  More Information

Study ID Numbers:   9361701225
First Received:   September 12, 2005
Last Updated:   September 26, 2007
ClinicalTrials.gov Identifier:   NCT00172679
Health Authority:   Taiwan: Department of Health

Keywords provided by National Taiwan University Hospital:
Tai Chi  
NK Cells  
T lymphocytes  
Exercise  

Study placed in the following topic categories:
Healthy

ClinicalTrials.gov processed this record on September 05, 2008




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