Quality of Life and Its Related Factors of Patients With Major Depressive Disorder

This study has been completed.
Sponsor:
Information provided by:
National Taiwan University Hospital
ClinicalTrials.gov Identifier:
NCT00172549
First received: September 12, 2005
Last updated: NA
Last verified: July 2005
History: No changes posted
  Purpose

The purpose of this study was to explore the quality of life and its related factors of patients with major depressive disorder. This study adopted cross-sectional research design. Purposive sampling was used to collect data from 120 patients came from the psychiatric outpatient departments of a medical center and a psychiatric hospital in northern Taiwan. Data were collected through structured questionnaires, which included:(1) demographic data sheet, (2) 5-item Brief Symptom Rating Scale (BSRS-5), (3) the Center For Epidemiologic Studies Depression Scale(CES-D), (4) Inventory of Socially Supportive Behaviors(ISSB), (5) World Health Organization’s Questionnaire on Quality of Life:BREF-Taiwan Version 100(WHOQOL-BREF). Data were analyzed by using SPSS/Windows 10.0 statistical software. The descriptive statistics methods included frequency distribution, arithmetic mean, standard deviation, and percentage. Data were analyzed by using independent t-test, Pearson’s product-moment correlation, one way ANOVA and stepwise multiple regression and so on, with which we can examine the demographic, degree of depression, social support and their links to the quality of life. Through the research, we found out the following results:

1.The condition of major depressive disorder patients’ quality of life is score range of each subtitle from 4-20. A sum from the following subtitles:physical domain is 11.54, psychological domain is 10.46, social domain is 11.61 and environmental domain is 12.82. The quality of life results is higher of environmental domain, which is poorer of psychological domain.

2. The results of quality of life related to demographic, degree of depression, social support were as followed:

  1. Physical domain:the independent variables of significant linear correlation is age, the age of early-onset, type of occupation, living arrangements, economic status, health status, the degree of depression and emotional support.
  2. Psychological domain:the independent variables of significant linear correlation is age, the age of early-onset, type of occupation, living arrangements, economic status, health status, the degree of depression, the sum of social support, emotional support, instrumental support, informational and appraisal support.
  3. Social domain:the independent variables of significant linear correlation is age, the age of early-onset, marital status, type of occupation, economic status, health status, the degree of depression, the sum of social support, emotional support, instrumental support, informational and appraisal support.
  4. Environmental domain:the independent variables of significant linear correlation is age, the age of early-onset, marital status, economic status, the degree of depression, the sum of social support and emotional support.

3.The best stepwise regression models of predicting major depressive disorder patients’ quality of life were as followed:

  1. Physical domain:the best predicting factor is the degree of depression, and accounted for explained 60.30﹪of the variance.
  2. Psychological domain:the best predicting factors are the degree of depression, the sum of social support, the age of early-onset, age more than 71 years old, and accounted for explained 76.50﹪of the variance.
  3. Social domain:the best predicting factors are the degree of depression, the age of early-onset, informational and appraisal support, unemployment and age more than 71 years old, and accounted for explained 53.80﹪of the variance.
  4. Environmental domain:the best predicting factors are the degree of depression, income less than one hundred thousand, income more than one hundred ten thousand and more than 71 years old, and accounted for explained 53.50﹪of the variance.

The results of this study could understand major depressive disorder patients’ quality of life condition and provide related research in the future, develop local data and health administration reference of foundation.


Condition Phase
Depression
Phase 1

Study Type: Observational
Study Design: Observational Model: Defined Population
Time Perspective: Cross-Sectional

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Further study details as provided by National Taiwan University Hospital:

Study Start Date: March 2004
Estimated Study Completion Date: October 2004
  Eligibility

Ages Eligible for Study:   18 Years and older
Genders Eligible for Study:   Female
Criteria

Inclusion Criteria:

  • people with Major Depressive Disorder

Exclusion Criteria:

-

  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT00172549

Sponsors and Collaborators
National Taiwan University Hospital
Investigators
Study Chair: Ping-Chuan Hsiung, Ph.D Department of Nursing, National Taiwan University
  More Information

No publications provided

ClinicalTrials.gov Identifier: NCT00172549     History of Changes
Other Study ID Numbers: 9361701176
Study First Received: September 12, 2005
Last Updated: September 12, 2005
Health Authority: Taiwan: Department of Health

Additional relevant MeSH terms:
Depression
Depressive Disorder
Depressive Disorder, Major
Behavioral Symptoms
Mood Disorders
Mental Disorders

ClinicalTrials.gov processed this record on August 21, 2014