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Role of Routine Nasogastric Decompression After Subtotal Gastrectomy

This study is currently recruiting participants.
Verified by Chinese University of Hong Kong, September 2005

Sponsored by: Chinese University of Hong Kong
Information provided by: Chinese University of Hong Kong
ClinicalTrials.gov Identifier: NCT00164918
  Purpose

The aim of the study is to evaluate whether subtotal gastrectomy without post-operative nasogastric decompression is better in terms of early post-operative bowel function and chest complication.


Condition Intervention Phase
Cancer of Stomach
Device: nasogastric tube
Phase III

MedlinePlus related topics:   Cancer    Stomach Cancer   

U.S. FDA Resources

Study Type:   Interventional
Study Design:   Treatment, Randomized, Open Label, Active Control, Parallel Assignment, Safety/Efficacy Study
Official Title:   Role of Routine Nasogastric Decompression After Subtotal Gastrectomy

Further study details as provided by Chinese University of Hong Kong:

Primary Outcome Measures:
  • Bowel function and related symptoms early post-op

Estimated Enrollment:   90
Study Start Date:   September 2004

Detailed Description:

Nasogastric decompression is an intra-operative routine in most of the time to facilitate exposure of operative field during elective subtotal gastrectomy, but whether it should be retained post-operatively is controversial. Nasogastric decompression helps to drain the gastric remnant in case there is edema around the gastrojejunostomy, ileus and delayed gastric emptying, which can theoretically relieve nausea and abdominal distension. Besides, it may help decrease diaphragmatic splintage and hence decrease chance of chest infection if ileus occurs. However, nasogastric intubation could cause patient discomfort; also it has been shown that it would cause gastroesophageal reflux which may be associated with chest complication. There have been studies showing that routine post-operative nasogastric decompression is not necessary for gastrectomy in general, but the role in subtotal gastrectomy for stomach cancer is not well defined.

  Eligibility
Ages Eligible for Study:   18 Weeks and older
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No

Criteria

Inclusion Criteria:All patients suffering from carcinoma of stomach, decided for operation

  • subtotal, D1/D2 dissection
  • palliative resection

Exclusion Criteria:

  • actively bleeding tumor
  • perforation of tumor
  • patient present with gastric outlet obstruction
  • combine organ excision
  • known diabetes with nephropathy
  Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00164918

Contacts
Contact: Enders K. W. Ng, MD     85226322627     endersng@surgery.cuhk.edu.hk    
Contact: Man Yee Yung, BN     85226322956     myyung@surgery.cuhk.edu.hk    

Locations
China
Surgical Ward, Prince of Wales Hospital     Recruiting
      Hong Kong, China
      Contact: Enders K.W. Ng, MD     85226322627     endersng@surgery.cuhk.edu.hk    
      Contact: Man Yee Yung, BN     85226322956     myyung@surgery.cuhk.edu.hk    
      Sub-Investigator: Chris K.W. Yau, MRCS (Ed)            
      Principal Investigator: Enders K.W. Ng, MD            

Sponsors and Collaborators
Chinese University of Hong Kong

Investigators
Principal Investigator:     Enders K.W. Ng, MD     Chinese University of Hong Kong    
  More Information

Study ID Numbers:   CRE-2004.311
First Received:   September 12, 2005
Last Updated:   September 12, 2005
ClinicalTrials.gov Identifier:   NCT00164918
Health Authority:   Hong Kong: Department of Health

Study placed in the following topic categories:
Stomach Diseases
Digestive System Diseases
Digestive System Neoplasms
Gastrointestinal Diseases
Stomach Neoplasms
Gastrointestinal Neoplasms
Stomach cancer

Additional relevant MeSH terms:
Neoplasms
Neoplasms by Site

ClinicalTrials.gov processed this record on August 21, 2008




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